CRCGN015_MCF10A_48H:G21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,4-dinitrotoluene 11.0 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

28 genes differentially expressed following the CRCGN015_MCF10A_48H:G21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STK25 serine/threonine kinase 25 5.09377
PPARG peroxisome proliferator-activated receptor gamma 4.43022
CCDC92 coiled-coil domain containing 92 4.24046
HYOU1 hypoxia up-regulated 1 4.07621
ANO10 anoctamin 10 3.98094
ACAA1 acetyl-CoA acyltransferase 1 3.689
CERK ceramide kinase 3.50303
PLEKHJ1 pleckstrin homology domain containing, family J member 1 3.30605
CDK19 cyclin-dependent kinase 19 3.19673
KCTD5 potassium channel tetramerization domain containing 5 2.51417
TGM4 transglutaminase 4 2.37912
SRGN serglycin 2.35372
CALB1 calbindin 1, 28kDa 2.16445
AGPS alkylglycerone phosphate synthase 2.16198
QARS1 glutaminyl-tRNA synthetase 1 2.12223
PTK6 protein tyrosine kinase 6 2.09912
CRNN cornulin 2.01596
KLK12 kallikrein-related peptidase 12 2.0019

decreased expression

Symbol Name Standardized Value
UFM1 ubiquitin-fold modifier 1 -5.0135
HEBP1 heme binding protein 1 -2.69127
RXYLT1 ribitol xylosyltransferase 1 -2.55967
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -2.46889
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit -2.43068
SYBU syntabulin (syntaxin-interacting) -2.31612
CYB5RL cytochrome b5 reductase-like -2.10658
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) -2.06632
FAM8A1 family with sequence similarity 8, member A1 -2.03892
SIGLEC15 sialic acid binding Ig-like lectin 15 -2.0019