CRCGN015_MCF10A_48H:G22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4,8-dihydroxy-2-quinolinecarboxylic acid 99.88 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN015_MCF10A_48H:G22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.92223
MAP2K5 mitogen-activated protein kinase kinase 5 2.56553
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.47358
SIRT3 sirtuin 3 2.4445
BZW2 basic leucine zipper and W2 domains 2 2.41169
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.17385
SNX11 sorting nexin 11 2.10625
RFX5 regulatory factor X, 5 (influences HLA class II expression) 2.04717

decreased expression

Symbol Name Standardized Value
TES testin LIM domain protein -3.26764
MSMO1 methylsterol monooxygenase 1 -3.05492
SNX7 sorting nexin 7 -2.66683
RND3 Rho family GTPase 3 -2.35302
BIRC2 baculoviral IAP repeat containing 2 -2.26859
TMEM123 transmembrane protein 123 -2.14908
PLK2 polo-like kinase 2 -2.14426