CRCGN015_MCF10A_48H:G23 Gene Set
Genes
45 genes differentially expressed following the CRCGN015_MCF10A_48H:G23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MCOLN1
|
mucolipin 1
|
4.13405
|
|
TLCD3A
|
TLC domain containing 3A
|
4.07121
|
|
GATA3
|
GATA binding protein 3
|
3.25109
|
|
HS3ST2
|
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
|
2.85758
|
|
ABCF1
|
ATP-binding cassette, sub-family F (GCN20), member 1
|
2.68231
|
|
C1R
|
complement component 1, r subcomponent
|
2.47922
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.37099
|
|
NOP2
|
NOP2 nucleolar protein
|
2.33723
|
|
MPHOSPH8
|
M-phase phosphoprotein 8
|
2.29783
|
|
CD8A
|
CD8a molecule
|
2.25267
|
|
NAGPA
|
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
|
2.22323
|
|
PNPLA6
|
patatin-like phospholipase domain containing 6
|
2.21442
|
|
C1S
|
complement component 1, s subcomponent
|
2.2095
|
|
PRPF19
|
pre-mRNA processing factor 19
|
2.15762
|
|
COG7
|
component of oligomeric golgi complex 7
|
2.14901
|
|
RIOX1
|
ribosomal oxygenase 1
|
2.14771
|
|
PACSIN2
|
protein kinase C and casein kinase substrate in neurons 2
|
2.12053
|
|
STAB1
|
stabilin 1
|
2.11271
|
|
CXCL12
|
chemokine (C-X-C motif) ligand 12
|
2.10382
|
|
NPL
|
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
|
2.07275
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.04494
|
|
QTRT1
|
queuine tRNA-ribosyltransferase 1
|
2.039
|
|
SIGLEC1
|
sialic acid binding Ig-like lectin 1, sialoadhesin
|
2.03143
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PRPF4
|
pre-mRNA processing factor 4
|
-4.47633
|
|
REEP5
|
receptor accessory protein 5
|
-3.95223
|
|
PLK2
|
polo-like kinase 2
|
-3.7451
|
|
KRT14
|
keratin 14, type I
|
-3.49186
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.39314
|
|
PDLIM1
|
PDZ and LIM domain 1
|
-3.2332
|
|
MSMO1
|
methylsterol monooxygenase 1
|
-2.98246
|
|
ANXA3
|
annexin A3
|
-2.97474
|
|
DCTN3
|
dynactin 3 (p22)
|
-2.56485
|
|
SLC16A4
|
solute carrier family 16, member 4
|
-2.54416
|
|
SACM1L
|
SAC1 suppressor of actin mutations 1-like (yeast)
|
-2.50244
|
|
SUZ12
|
SUZ12 polycomb repressive complex 2 subunit
|
-2.39155
|
|
RHOT1
|
ras homolog family member T1
|
-2.26772
|
|
POLE3
|
polymerase (DNA directed), epsilon 3, accessory subunit
|
-2.2417
|
|
PSMB7
|
proteasome (prosome, macropain) subunit, beta type, 7
|
-2.219
|
|
OSBPL9
|
oxysterol binding protein-like 9
|
-2.16338
|
|
ATP6V1G1
|
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
|
-2.15608
|
|
TMED1
|
transmembrane emp24 protein transport domain containing 1
|
-2.11818
|
|
LDHB
|
lactate dehydrogenase B
|
-2.10257
|
|
EDF1
|
endothelial differentiation-related factor 1
|
-2.08395
|
|
GRHPR
|
glyoxylate reductase/hydroxypyruvate reductase
|
-2.06081
|
|
ILK
|
integrin-linked kinase
|
-2.03727
|
