CRCGN015_MCF10A_48H:H02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 3,3'-dimethoxybenzidine.2hcl 33.82 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN015_MCF10A_48H:H02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 5.06704
SNX11 sorting nexin 11 2.84689
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.66713
S100A4 S100 calcium binding protein A4 2.50074
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.41614
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.28529
NXT1 nuclear transport factor 2-like export factor 1 2.14789
TRIM13 tripartite motif containing 13 2.08153
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 2.03014
HDHD5 haloacid dehalogenase like hydrolase domain containing 5 2.00867

decreased expression

Symbol Name Standardized Value
ANXA3 annexin A3 -3.96601
MELK maternal embryonic leucine zipper kinase -3.4184
TM9SF3 transmembrane 9 superfamily member 3 -2.99542
HPRT1 hypoxanthine phosphoribosyltransferase 1 -2.48584
VTI1B vesicle transport through interaction with t-SNAREs 1B -2.26051
TNIP1 TNFAIP3 interacting protein 1 -2.17736
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -2.09681
ATP13A2 ATPase type 13A2 -2.00158