CRCGN015_MCF10A_48H:H03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 3,3'-dimethoxybenzidine.2hcl 11.27 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

1062 genes differentially expressed following the CRCGN015_MCF10A_48H:H03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AMDHD2 amidohydrolase domain containing 2 9.4955
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 5.75418
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 5.24783
AXIN1 axin 1 4.85939
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 4.78148
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 4.77193
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) 4.33682
CGB8 chorionic gonadotropin, beta polypeptide 8 4.33666
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K 4.05479
MORN1 MORN repeat containing 1 4.04346
TBL3 transducin (beta)-like 3 4.02447
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 3.8881
DGCR6L DiGeorge syndrome critical region gene 6-like 3.81987
SCT secretin 3.7743
CLDN9 claudin 9 3.67617
ZNF205 zinc finger protein 205 3.67086
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 3.65546
NKX6-1 NK6 homeobox 1 3.65048
CEP131 centrosomal protein 131kDa 3.58684
ZNF787 zinc finger protein 787 3.58487
MTNAP1 mitochondrial nucleoid associated protein 1 3.58056
KRT86 keratin 86, type II 3.54972
KIFBP kinesin family binding protein 3.5337
AFF3 AF4/FMR2 family, member 3 3.49095
RAB40C RAB40C, member RAS oncogene family 3.48992
CERT1 ceramide transporter 1 3.48842
NPAS1 neuronal PAS domain protein 1 3.4732
MTSS2 MTSS I-BAR domain containing 2 3.46063
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 3.45035
USP20 ubiquitin specific peptidase 20 3.43476
PCYT2 phosphate cytidylyltransferase 2, ethanolamine 3.43438
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 3.43221
HAAO 3-hydroxyanthranilate 3,4-dioxygenase 3.4154
MED15 mediator complex subunit 15 3.40496
HOXB3 homeobox B3 3.40157
ARMC7 armadillo repeat containing 7 3.31905
CADM4 cell adhesion molecule 4 3.31421
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 3.31163
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 3.3065
PNMA3 paraneoplastic Ma antigen 3 3.3044
VRTN vertebrae development associated 3.30271
LIME1 Lck interacting transmembrane adaptor 1 3.28539
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 3.27247
SSTR5 somatostatin receptor 5 3.2712
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 3.24934
GCDH glutaryl-CoA dehydrogenase 3.24428
ADGRB1 adhesion G protein-coupled receptor B1 3.24322
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 3.23737
PRICKLE3 prickle homolog 3 (Drosophila) 3.23052
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 3.22853
METTL25B methyltransferase like 25B 3.22811
BCL7A B-cell CLL/lymphoma 7A 3.22546
USP18 ubiquitin specific peptidase 18 3.22442
CCDC85B coiled-coil domain containing 85B 3.21874
ZNF282 zinc finger protein 282 3.21753
POLL polymerase (DNA directed), lambda 3.21025
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 3.20613
PECR peroxisomal trans-2-enoyl-CoA reductase 3.20379
INO80B INO80 complex subunit B 3.19949
KRI1 KRI1 homolog (S. cerevisiae) 3.1728
NR1I3 nuclear receptor subfamily 1, group I, member 3 3.17046
RNLS renalase, FAD-dependent amine oxidase 3.14728
B3GAT3 beta-1,3-glucuronyltransferase 3 3.13945
CD160 CD160 molecule 3.13862
MKNK1 MAP kinase interacting serine/threonine kinase 1 3.1291
PAGE4 P antigen family, member 4 (prostate associated) 3.12626
HROB homologous recombination factor with OB-fold 3.12516
LAX1 lymphocyte transmembrane adaptor 1 3.12389
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 3.12224
OBP2B odorant binding protein 2B 3.11222
PCDHB13 protocadherin beta 13 3.1106
TP53BP2 tumor protein p53 binding protein 2 3.09466
PDE11A phosphodiesterase 11A 3.09228
NT5C 5', 3'-nucleotidase, cytosolic 3.0896
MATK megakaryocyte-associated tyrosine kinase 3.08921
RMDN3 regulator of microtubule dynamics 3 3.08142
IBSP integrin-binding sialoprotein 3.07999
SH3GLB2 SH3-domain GRB2-like endophilin B2 3.07985
GALK1 galactokinase 1 3.07629
NKG7 natural killer cell granule protein 7 3.06839
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) 3.06807
MYL10 myosin, light chain 10, regulatory 3.06487
CNTFR ciliary neurotrophic factor receptor 3.06302
PDCD1 programmed cell death 1 3.05747
TMEM132A transmembrane protein 132A 3.05057
CHRND cholinergic receptor, nicotinic, delta (muscle) 3.04614
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 3.04458
CLCN7 chloride channel, voltage-sensitive 7 3.04195
PLPP3 phospholipid phosphatase 3 3.04158
ALG12 ALG12, alpha-1,6-mannosyltransferase 3.03905
RAB27A RAB27A, member RAS oncogene family 3.03348
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2 3.03283
HDAC5 histone deacetylase 5 3.03241
MREG melanoregulin 3.02356
NKX2-5 NK2 homeobox 5 3.02286
CBARP CACN subunit beta associated regulatory protein 3.02032
KCNIP2 Kv channel interacting protein 2 3.01757
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 3.01444
MYL5 myosin, light chain 5, regulatory 3.01342
ZNF174 zinc finger protein 174 3.01166
CLSTN3 calsyntenin 3 3.00952
SSBP3 single stranded DNA binding protein 3 3.0061
DGCR2 DiGeorge syndrome critical region gene 2 3.0043
GRM1 glutamate receptor, metabotropic 1 3.00333
CDHR5 cadherin-related family member 5 3.00242
ZBTB7B zinc finger and BTB domain containing 7B 3.00219
BCL2L10 BCL2-like 10 (apoptosis facilitator) 3.00161
CDHR2 cadherin-related family member 2 2.98769
CCDC134 coiled-coil domain containing 134 2.98415
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 2.98254
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 2.97873
HAND1 heart and neural crest derivatives expressed 1 2.97242
RENBP renin binding protein 2.96901
ZBTB32 zinc finger and BTB domain containing 32 2.96806
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 2.96616
IL2RB interleukin 2 receptor, beta 2.96587
TRIM11 tripartite motif containing 11 2.95808
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 2.95776
SLCO5A1 solute carrier organic anion transporter family, member 5A1 2.9483
NLGN1 neuroligin 1 2.94656
AMN amnion associated transmembrane protein 2.94134
APOA4 apolipoprotein A-IV 2.93981
CXCR5 chemokine (C-X-C motif) receptor 5 2.93899
VSX1 visual system homeobox 1 2.93898
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.93625
WNT7B wingless-type MMTV integration site family, member 7B 2.9333
ITPKA inositol-trisphosphate 3-kinase A 2.93322
GPR27 G protein-coupled receptor 27 2.93216
SAMD14 sterile alpha motif domain containing 14 2.92678
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 2.92125
GBX2 gastrulation brain homeobox 2 2.91889
MYH13 myosin, heavy chain 13, skeletal muscle 2.91188
CLCN1 chloride channel, voltage-sensitive 1 2.90811
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 2.9052
ADGRL3 adhesion G protein-coupled receptor L3 2.90316
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 2.89405
FAAP100 FA core complex associated protein 100 2.89371
THAP7 THAP domain containing 7 2.88919
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 2.88873
CRYBB1 crystallin, beta B1 2.88779
TTC38 tetratricopeptide repeat domain 38 2.88661
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 2.88601
FAM246A family with sequence similarity 246 member A 2.87882
TOP3B topoisomerase (DNA) III beta 2.878
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 2.87568
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) 2.86954
HAND2 heart and neural crest derivatives expressed 2 2.86892
ADAM10 ADAM metallopeptidase domain 10 2.86447
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 2.86273
KLHL22 kelch-like family member 22 2.86139
H2AC25 H2A clustered histone 25 2.85689
ZSCAN2 zinc finger and SCAN domain containing 2 2.85156
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein 2.84229
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 2.84164
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 2.83673
GPR31 G protein-coupled receptor 31 2.83633
CT55 cancer/testis antigen 55 2.8285
ARSD arylsulfatase D 2.8252
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 2.82261
PAX6 paired box 6 2.82002
HRH2 histamine receptor H2 2.81886
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 2.81883
USP27X ubiquitin specific peptidase 27, X-linked 2.81814
TLX1 T-cell leukemia homeobox 1 2.81745
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 2.81432
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 2.81139
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 2.80617
EMID1 EMI domain containing 1 2.80347
AKT2 v-akt murine thymoma viral oncogene homolog 2 2.80072
STMN3 stathmin-like 3 2.79776
DUX4 double homeobox 4 2.79398
IQCC IQ motif containing C 2.79321
SRPK3 SRSF protein kinase 3 2.79132
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 2.79014
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 2.78955
ALPG alkaline phosphatase, germ cell 2.78915
E4F1 E4F transcription factor 1 2.78871
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 2.78684
NKRF NFKB repressing factor 2.78541
CD8A CD8a molecule 2.78427
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 2.78375
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 2.78003
TFEC transcription factor EC 2.77793
TRIM3 tripartite motif containing 3 2.77546
TRPM2 transient receptor potential cation channel, subfamily M, member 2 2.76748
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 2.76428
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 2.75785
PDIA2 protein disulfide isomerase family A, member 2 2.75333
TRMT61A tRNA methyltransferase 61A 2.75202
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 2.74956
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 2.7461
CST7 cystatin F (leukocystatin) 2.74505
GPKOW G patch domain and KOW motifs 2.74395
BIN2 bridging integrator 2 2.74353
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I 2.74308
MYBPC3 myosin binding protein C, cardiac 2.7363
CD8B CD8b molecule 2.73601
APOM apolipoprotein M 2.73295
IFT140 intraflagellar transport 140 2.73009
ZBTB14 zinc finger and BTB domain containing 14 2.72324
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.7221
JPH2 junctophilin 2 2.72162
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 2.72124
FLT3LG fms-related tyrosine kinase 3 ligand 2.71957
ATP8B4 ATPase, class I, type 8B, member 4 2.71692
CCDC57 coiled-coil domain containing 57 2.71104
HDHD5 haloacid dehalogenase like hydrolase domain containing 5 2.70794
ASMT acetylserotonin O-methyltransferase 2.70527
IMPG2 interphotoreceptor matrix proteoglycan 2 2.70385
PHF13 PHD finger protein 13 2.70322
NOL11 nucleolar protein 11 2.70003
PKLR pyruvate kinase, liver and RBC 2.69999
CAMK2B calcium/calmodulin-dependent protein kinase II beta 2.6978
PAX3 paired box 3 2.69685
BCL2 B-cell CLL/lymphoma 2 2.69555
WIF1 WNT inhibitory factor 1 2.69397
A4GALT alpha 1,4-galactosyltransferase 2.69229
SLC26A1 solute carrier family 26 (anion exchanger), member 1 2.68994
RORB RAR-related orphan receptor B 2.68946
RHOH ras homolog family member H 2.68808
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 2.68797
AMPH amphiphysin 2.68667
ZNF365 zinc finger protein 365 2.68513
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 2.6849
CCL24 chemokine (C-C motif) ligand 24 2.68253
HAGH hydroxyacylglutathione hydrolase 2.68039
RRAGA Ras-related GTP binding A 2.6763
RNF125 ring finger protein 125, E3 ubiquitin protein ligase 2.66825
BAAT bile acid CoA:amino acid N-acyltransferase 2.66442
PRKCB protein kinase C, beta 2.66304
VPS9D1 VPS9 domain containing 1 2.66168
EGR4 early growth response 4 2.65914
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) 2.65876
SLC45A2 solute carrier family 45, member 2 2.65653
SACK1E scaffolding CK1 anchoring protein E 2.6464
PRR7 proline rich 7 (synaptic) 2.64461
ERCC2 excision repair cross-complementation group 2 2.64149
RAX retina and anterior neural fold homeobox 2.63961
IKZF4 IKAROS family zinc finger 4 (Eos) 2.63786
MKRN3 makorin ring finger protein 3 2.63531
ETV7 ets variant 7 2.62859
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 2.62761
POU3F2 POU class 3 homeobox 2 2.62732
LIPC lipase, hepatic 2.62703
KIF25 kinesin family member 25 2.62556
TREH trehalase (brush-border membrane glycoprotein) 2.62538
CAMK1 calcium/calmodulin-dependent protein kinase I 2.62537
ALG6 ALG6, alpha-1,3-glucosyltransferase 2.62183
TMEM187 transmembrane protein 187 2.62099
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 2.62038
ELP4 elongator acetyltransferase complex subunit 4 2.61726
RAP2A RAP2A, member of RAS oncogene family 2.61503
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 2.61004
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 2.60916
SIRT1 sirtuin 1 2.60716
OR5I1 olfactory receptor, family 5, subfamily I, member 1 2.6068
FGGY FGGY carbohydrate kinase domain containing 2.60349
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 2.60086
SOCS1 suppressor of cytokine signaling 1 2.5944
DCC DCC netrin 1 receptor 2.59418
ZNF74 zinc finger protein 74 2.59292
CUTA cutA divalent cation tolerance homolog (E. coli) 2.58894
MRPL4 mitochondrial ribosomal protein L4 2.58696
CDH22 cadherin 22, type 2 2.58581
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 2.58347
CABP2 calcium binding protein 2 2.58159
PARVB parvin, beta 2.57919
MGAM maltase-glucoamylase 2.57903
SMAD7 SMAD family member 7 2.57787
ADORA1 adenosine A1 receptor 2.57623
INPP5J inositol polyphosphate-5-phosphatase J 2.57258
GPR183 G protein-coupled receptor 183 2.57127
CDADC1 cytidine and dCMP deaminase domain containing 1 2.57068
ODAD2 outer dynein arm docking complex subunit 2 2.56937
CNPY4 canopy FGF signaling regulator 4 2.56911
KHK ketohexokinase (fructokinase) 2.56623
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 2.56538
CCL5 chemokine (C-C motif) ligand 5 2.56478
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 2.56137
PTCH1 patched 1 2.5603
CXCR3 chemokine (C-X-C motif) receptor 3 2.55905
MAPK6 mitogen-activated protein kinase 6 2.5539
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 2.55379
TLE6 transducin-like enhancer of split 6 2.55295
TEF thyrotrophic embryonic factor 2.55273
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 2.54927
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 2.54916
PDE1B phosphodiesterase 1B, calmodulin-dependent 2.549
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal 2.54732
CCDC22 coiled-coil domain containing 22 2.5397
SYP synaptophysin 2.5396
CCDC86 coiled-coil domain containing 86 2.53868
GKN1 gastrokine 1 2.53206
RXRA retinoid X receptor, alpha 2.53159
HHLA2 HERV-H LTR-associating 2 2.53107
SPAG8 sperm associated antigen 8 2.52825
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 2.52742
ALPP alkaline phosphatase, placental 2.52738
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 2.52616
SORBS1 sorbin and SH3 domain containing 1 2.52278
TSPAN9 tetraspanin 9 2.52016
XYLB xylulokinase homolog (H. influenzae) 2.5178
IL18RAP interleukin 18 receptor accessory protein 2.51645
RFXAP regulatory factor X-associated protein 2.5158
CPLX2 complexin 2 2.51475
KLRD1 killer cell lectin-like receptor subfamily D, member 1 2.5146
TRIP6 thyroid hormone receptor interactor 6 2.51448
PSPN persephin 2.51376
GDF9 growth differentiation factor 9 2.51356
MAPK4 mitogen-activated protein kinase 4 2.51257
MATN4 matrilin 4 2.50532
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like 2.50462
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 2.50447
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) 2.5035
HLA-DOA major histocompatibility complex, class II, DO alpha 2.50084
BIRC7 baculoviral IAP repeat containing 7 2.49742
ACO2 aconitase 2, mitochondrial 2.49539
TRIB2 tribbles pseudokinase 2 2.49434
RBM15B RNA binding motif protein 15B 2.49283
ASIC4 acid sensing (proton gated) ion channel family member 4 2.49146
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 2.48708
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 2.48687
ANTKMT adenine nucleotide translocase lysine methyltransferase 2.48485
BCL2L13 BCL2-like 13 (apoptosis facilitator) 2.48313
PKD1 polycystic kidney disease 1 (autosomal dominant) 2.48295
TBC1D22B TBC1 domain family, member 22B 2.48106
LGMN legumain 2.48085
WBP2 WW domain binding protein 2 2.48073
RNF208 ring finger protein 208 2.48028
COL13A1 collagen, type XIII, alpha 1 2.48007
SSTR1 somatostatin receptor 1 2.47689
RGS9BP regulator of G protein signaling 9 binding protein 2.47639
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 2.47576
LMF1 lipase maturation factor 1 2.47475
TSPO2 translocator protein 2 2.47277
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 2.47245
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 2.46947
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 2.46831
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 2.46792
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 2.46546
KLRC4-KLRK1 KLRC4-KLRK1 readthrough 2.46338
PRMT7 protein arginine methyltransferase 7 2.4617
MTNR1B melatonin receptor 1B 2.46081
RNF216 ring finger protein 216 2.46058
NCR3 natural cytotoxicity triggering receptor 3 2.45781
TAOK2 TAO kinase 2 2.45774
TRPV6 transient receptor potential cation channel, subfamily V, member 6 2.4577
GAGE1 G antigen 1 2.45708
FUZ fuzzy planar cell polarity protein 2.45686
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 2.45151
HNRNPCL1 heterogeneous nuclear ribonucleoprotein C-like 1 2.44826
SLC30A10 solute carrier family 30, member 10 2.44559
CXCL13 chemokine (C-X-C motif) ligand 13 2.44366
GJA3 gap junction protein, alpha 3, 46kDa 2.44042
TTLL1 tubulin tyrosine ligase-like family member 1 2.43932
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 2.43897
LGALS14 lectin, galactoside-binding, soluble, 14 2.43466
EPHX2 epoxide hydrolase 2, cytoplasmic 2.43286
ITPK1 inositol-tetrakisphosphate 1-kinase 2.43238
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 2.42996
MEP1B meprin A, beta 2.4276
FBXL15 F-box and leucine-rich repeat protein 15 2.4265
NPAS3 neuronal PAS domain protein 3 2.42634
CDK3 cyclin-dependent kinase 3 2.4234
HAPLN1 hyaluronan and proteoglycan link protein 1 2.42126
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 2.42005
CCDC106 coiled-coil domain containing 106 2.41947
SIRT7 sirtuin 7 2.41838
ACE angiotensin I converting enzyme 2.41806
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 2.41772
SPEG SPEG complex locus 2.41766
RAB26 RAB26, member RAS oncogene family 2.41644
TAAR2 trace amine associated receptor 2 2.41427
GRAP2 GRB2-related adaptor protein 2 2.41281
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 2.4096
CHRD chordin 2.40836
PGM5 phosphoglucomutase 5 2.40714
EHMT2 euchromatic histone-lysine N-methyltransferase 2 2.40398
HMGXB3 HMG box domain containing 3 2.40348
EXD3 exonuclease 3'-5' domain containing 3 2.40333
ZNF671 zinc finger protein 671 2.40009
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 2.39971
TMEM259 transmembrane protein 259 2.39848
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.39825
KLRB1 killer cell lectin-like receptor subfamily B, member 1 2.39664
ECI1 enoyl-CoA delta isomerase 1 2.39521
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae) 2.3939
TDRD1 tudor domain containing 1 2.38984
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 2.38846
MEPE matrix extracellular phosphoglycoprotein 2.38686
SOX13 SRY (sex determining region Y)-box 13 2.38488
POLRMT polymerase (RNA) mitochondrial (DNA directed) 2.38399
ASB4 ankyrin repeat and SOCS box containing 4 2.38296
RCAN3 RCAN family member 3 2.38081
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 2.38076
FOXN2 forkhead box N2 2.37982
ZNF146 zinc finger protein 146 2.37977
RND1 Rho family GTPase 1 2.37836
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 2.37819
SPATA31C1 SPATA31 subfamily C, member 1 2.37579
CD180 CD180 molecule 2.37394
TRAPPC6A trafficking protein particle complex 6A 2.37294
LBX1 ladybird homeobox 1 2.37168
DHRS11 dehydrogenase/reductase (SDR family) member 11 2.36815
SH2D1A SH2 domain containing 1A 2.36775
MECR mitochondrial trans-2-enoyl-CoA reductase 2.36756
TP53I11 tumor protein p53 inducible protein 11 2.36678
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 2.3659
AGBL2 ATP/GTP binding protein-like 2 2.36541
SPTBN2 spectrin, beta, non-erythrocytic 2 2.36497
GZMM granzyme M (lymphocyte met-ase 1) 2.36308
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 2.36235
NEUROD4 neuronal differentiation 4 2.36188
CRYM crystallin, mu 2.36072
SHPK sedoheptulokinase 2.36026
FGF8 fibroblast growth factor 8 (androgen-induced) 2.35753
NTN3 netrin 3 2.35685
HRH3 histamine receptor H3 2.35598
KLHL1 kelch-like family member 1 2.35437
GSK3A glycogen synthase kinase 3 alpha 2.35094
EDA2R ectodysplasin A2 receptor 2.34873
SOX14 SRY (sex determining region Y)-box 14 2.34765
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like 2.34608
SNCB synuclein, beta 2.34445
ZG16 zymogen granule protein 16 2.34364
FOXL1 forkhead box L1 2.34349
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 2.34302
EPHB6 EPH receptor B6 2.34182
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) 2.34115
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 2.33896
SGF29 SAGA complex associated factor 29 2.33451
NCAPH2 non-SMC condensin II complex, subunit H2 2.3343
B9D1 B9 protein domain 1 2.33253
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 2.33238
RNF115 ring finger protein 115 2.33157
RRAGB Ras-related GTP binding B 2.33138
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 2.33027
DCAKD dephospho-CoA kinase domain containing 2.3278
RASA3 RAS p21 protein activator 3 2.32447
GRM2 glutamate receptor, metabotropic 2 2.32442
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 2.32334
HDAC11 histone deacetylase 11 2.32159
EPHA5 EPH receptor A5 2.32102
HEXA hexosaminidase A (alpha polypeptide) 2.32018
CDKN2AIP CDKN2A interacting protein 2.31875
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 2.31873
SLC17A4 solute carrier family 17, member 4 2.31786
MRTFB myocardin related transcription factor B 2.31765
ZNF148 zinc finger protein 148 2.31718
FN3K fructosamine 3 kinase 2.31467
PQBP1 polyglutamine binding protein 1 2.31281
OR7C1 olfactory receptor, family 7, subfamily C, member 1 2.31272
CXCR6 chemokine (C-X-C motif) receptor 6 2.31195
RBM38 RNA binding motif protein 38 2.31158
TMSB4Y thymosin beta 4, Y-linked 2.3081
TBX4 T-box 4 2.30755
TSPAN32 tetraspanin 32 2.30695
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 2.30683
TPST2 tyrosylprotein sulfotransferase 2 2.30576
ANKRD44 ankyrin repeat domain 44 2.30397
LGALS3 lectin, galactoside-binding, soluble, 3 2.30246
OSGIN1 oxidative stress induced growth inhibitor 1 2.30201
CATSPERH catsper channel auxiliary subunit eta 2.3008
SLCO4C1 solute carrier organic anion transporter family, member 4C1 2.2993
KLHL36 kelch-like family member 36 2.29926
IRF2 interferon regulatory factor 2 2.29691
NRG2 neuregulin 2 2.29586
PHGDH phosphoglycerate dehydrogenase 2.29561
CHKA choline kinase alpha 2.29133
PBLD phenazine biosynthesis-like protein domain containing 2.29089
ACAD10 acyl-CoA dehydrogenase family, member 10 2.29059
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 2.28997
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q 2.2896
CCIN calicin 2.28943
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.28859
ITGB7 integrin, beta 7 2.28781
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 2.28737
NEURL1 neuralized E3 ubiquitin protein ligase 1 2.28706
OSBP2 oxysterol binding protein 2 2.28663
ARHGAP28 Rho GTPase activating protein 28 2.28662
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 2.2856
SF3B4 splicing factor 3b, subunit 4, 49kDa 2.28302
SOX1 SRY (sex determining region Y)-box 1 2.28162
TP53TG5 TP53 target 5 2.2808
AMBN ameloblastin (enamel matrix protein) 2.28032
TRPM3 transient receptor potential cation channel, subfamily M, member 3 2.27827
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 2.27759
POU3F4 POU class 3 homeobox 4 2.27726
LOC102723996 ICOS ligand 2.277
ZXDA zinc finger, X-linked, duplicated A 2.27542
SRRM5 serine/arginine repetitive matrix 5 2.27484
SNN stannin 2.27341
LCN1 lipocalin 1 2.27305
HPSE2 heparanase 2 (inactive) 2.27197
CER1 cerberus 1, DAN family BMP antagonist 2.2713
AKAP7 A kinase (PRKA) anchor protein 7 2.27069
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 2.26904
PYCR3 pyrroline-5-carboxylate reductase 3 2.26824
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 2.26664
GFI1B growth factor independent 1B transcription repressor 2.26464
SDK2 sidekick cell adhesion molecule 2 2.26376
LGSN lengsin, lens protein with glutamine synthetase domain 2.26366
WDR33 WD repeat domain 33 2.26277
TMEM120B transmembrane protein 120B 2.26226
WNT6 wingless-type MMTV integration site family, member 6 2.26207
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa 2.26198
AMOT angiomotin 2.26029
LRRC61 leucine rich repeat containing 61 2.25589
MBTPS1 membrane-bound transcription factor peptidase, site 1 2.25496
TESPA1 thymocyte expressed, positive selection associated 1 2.2547
ZIC4 Zic family member 4 2.25442
OSBPL7 oxysterol binding protein-like 7 2.25402
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 2.25309
VPS50 VPS50 subunit of EARP/GARPII complex 2.25122
TREML2 triggering receptor expressed on myeloid cells-like 2 2.25103
ZFPM1 zinc finger protein, FOG family member 1 2.25084
ZNF480 zinc finger protein 480 2.25083
CPLANE2 ciliogenesis and planar polarity effector complex subunit 2 2.24908
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 2.24717
OTOR otoraplin 2.24708
PTPRS protein tyrosine phosphatase, receptor type, S 2.24583
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) 2.24486
RPL10A ribosomal protein L10a 2.24479
LTF lactotransferrin 2.24443
SYMPK symplekin 2.24387
PLCL2 phospholipase C-like 2 2.242
HS1BP3 HCLS1 binding protein 3 2.24026
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 2.23968
CES3 carboxylesterase 3 2.23767
LDHC lactate dehydrogenase C 2.23691
MASP2 mannan-binding lectin serine peptidase 2 2.23649
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 2.23547
KLF13 Kruppel-like factor 13 2.234
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 2.23352
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) 2.23312
DTNB dystrobrevin, beta 2.2315
ADRA1D adrenoceptor alpha 1D 2.22913
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 2.22815
GBA1 glucosylceramidase beta 1 2.22709
RGS20 regulator of G-protein signaling 20 2.22686
IHH indian hedgehog 2.22582
GBX1 gastrulation brain homeobox 1 2.22526
SIX6 SIX homeobox 6 2.22507
ELOVL5 ELOVL fatty acid elongase 5 2.225
LMAN1L lectin, mannose-binding, 1 like 2.2245
ZBTB22 zinc finger and BTB domain containing 22 2.22402
EYA2 EYA transcriptional coactivator and phosphatase 2 2.22315
TPSD1 tryptase delta 1 2.22216
MAP3K10 mitogen-activated protein kinase kinase kinase 10 2.21992
CRX cone-rod homeobox 2.21948
NFE2 nuclear factor, erythroid 2 2.21869
SPACA1 sperm acrosome associated 1 2.21695
CYTH3 cytohesin 3 2.21479
BTBD2 BTB (POZ) domain containing 2 2.21426
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma 2.21312
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase 2.21299
LMTK2 lemur tyrosine kinase 2 2.21298
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) 2.21191
CASS4 Cas scaffolding protein family member 4 2.21125
HIC1 hypermethylated in cancer 1 2.21123
FSHB follicle stimulating hormone, beta polypeptide 2.20979
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 2.20945
LYRM9 LYR motif containing 9 2.20797
FCMR Fc fragment of IgM receptor 2.20782
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 2.20656
NSG2 neuronal vesicle trafficking associated 2 2.20581
DMPK dystrophia myotonica-protein kinase 2.20465
CCL16 chemokine (C-C motif) ligand 16 2.20313
ADAMDEC1 ADAM-like, decysin 1 2.20295
CEMP1 cementum protein 1 2.20254
UBTF upstream binding transcription factor, RNA polymerase I 2.20252
RUBCN rubicon autophagy regulator 2.20235
RAG2 recombination activating gene 2 2.20096
PTGDR2 prostaglandin D2 receptor 2 2.19996
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 2.19862
CD7 CD7 molecule 2.19802
TRIM49D2 tripartite motif containing 49D2 2.19769
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 2.19389
CLCA1 chloride channel accessory 1 2.19378
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 2.19346
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 2.1934
H2AC11 H2A clustered histone 11 2.19193
SLC12A9 solute carrier family 12, member 9 2.19119
TDRKH tudor and KH domain containing 2.19089
KDM8 lysine (K)-specific demethylase 8 2.19077
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 2.19025
CSNK1D casein kinase 1, delta 2.18736
HPCA hippocalcin 2.18723
DEAF1 DEAF1 transcription factor 2.18294
ZNF460 zinc finger protein 460 2.18133
HNMT histamine N-methyltransferase 2.17974
IL12A interleukin 12A 2.17974
HPS1 Hermansky-Pudlak syndrome 1 2.1796
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 2.17784
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 2.17705
AMELY amelogenin, Y-linked 2.17687
ZNF76 zinc finger protein 76 2.17686
LMO1 LIM domain only 1 (rhombotin 1) 2.17671
TAC4 tachykinin 4 (hemokinin) 2.17643
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 2.17588
KCTD13 potassium channel tetramerization domain containing 13 2.17491
GPR162 G protein-coupled receptor 162 2.17489
NMUR1 neuromedin U receptor 1 2.17435
GPR88 G protein-coupled receptor 88 2.17411
HPR haptoglobin-related protein 2.17393
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 2.17285
FGF17 fibroblast growth factor 17 2.17244
DTWD1 DTW domain containing 1 2.17157
PTCD1 pentatricopeptide repeat domain 1 2.17123
HOXD13 homeobox D13 2.17074
FAM3C family with sequence similarity 3, member C 2.16967
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 2.1689
DUSP14 dual specificity phosphatase 14 2.16874
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 2.1685
CA5A carbonic anhydrase VA, mitochondrial 2.16838
NARS1 asparaginyl-tRNA synthetase 1 2.16816
IFT54 intraflagellar transport 54 2.16811
MAN1B1 mannosidase, alpha, class 1B, member 1 2.1678
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 2.16773
PRODH proline dehydrogenase (oxidase) 1 2.16728
AARS1 alanyl-tRNA synthetase 1 2.16674
NPTN neuroplastin 2.16659
IL9R interleukin 9 receptor 2.16562
ALAS2 5'-aminolevulinate synthase 2 2.16556
F13B coagulation factor XIII, B polypeptide 2.16504
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 2.16469
TMEM160 transmembrane protein 160 2.16414
H2BC3 H2B clustered histone 3 2.16375
JPH3 junctophilin 3 2.15841
ATXN7L1 ataxin 7-like 1 2.1581
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 2.15808
MITF microphthalmia-associated transcription factor 2.15602
IL7 interleukin 7 2.15582
ETHE1 ethylmalonic encephalopathy 1 2.1558
STAG2 stromal antigen 2 2.15557
SYTL2 synaptotagmin-like 2 2.15403
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 2.15376
SPEF1 sperm flagellar 1 2.15345
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 2.15204
PCDHB12 protocadherin beta 12 2.15164
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B 2.15164
NUP133 nucleoporin 133kDa 2.15149
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 2.15103
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 2.1493
DLX6 distal-less homeobox 6 2.14761
CCDC70 coiled-coil domain containing 70 2.1476
P3H3 prolyl 3-hydroxylase 3 2.14719
EXTL3 exostosin-like glycosyltransferase 3 2.14476
CRYGB crystallin, gamma B 2.14462
ASL argininosuccinate lyase 2.1437
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 2.14364
DEPDC5 DEP domain containing 5 2.14344
STOML1 stomatin (EPB72)-like 1 2.14344
PHF7 PHD finger protein 7 2.14338
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains 2.14304
GSTT4 glutathione S-transferase theta 4 2.14278
PIPOX pipecolic acid oxidase 2.14177
HSFX2 heat shock transcription factor family, X linked 2 2.14097
TBC1D10B TBC1 domain family, member 10B 2.14057
PTP4A3 protein tyrosine phosphatase type IVA, member 3 2.14042
ATOX1 antioxidant 1 copper chaperone 2.14015
MAGEA8 melanoma antigen family A8 2.13986
ZNHIT2 zinc finger, HIT-type containing 2 2.13893
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.13834
WNT3 wingless-type MMTV integration site family, member 3 2.13831
GNLY granulysin 2.13706
SCN3A sodium channel, voltage gated, type III alpha subunit 2.13541
ADGRD2 adhesion G protein-coupled receptor D2 2.13449
KRT3 keratin 3, type II 2.13386
ZFPL1 zinc finger protein-like 1 2.13372
OR7E24 olfactory receptor, family 7, subfamily E, member 24 2.13227
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 2.13112
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 2.12906
ARHGAP35 Rho GTPase activating protein 35 2.12872
HYDIN HYDIN, axonemal central pair apparatus protein 2.12768
TMEM50A transmembrane protein 50A 2.12768
PPP1R2C PPP1R2C family member C 2.12755
DNAAF8 dynein axonemal assembly factor 8 2.12741
RAMP1 receptor (G protein-coupled) activity modifying protein 1 2.12685
KHSRP KH-type splicing regulatory protein 2.12679
ADM2 adrenomedullin 2 2.12673
CD84 CD84 molecule 2.12666
TRPM8 transient receptor potential cation channel, subfamily M, member 8 2.12632
ANKZF1 ankyrin repeat and zinc finger domain containing 1 2.12583
LY6G5C lymphocyte antigen 6 complex, locus G5C 2.12482
ATG12 autophagy related 12 2.12439
ADRA2C adrenoceptor alpha 2C 2.1238
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 2.12359
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 2.12226
CSF1 colony stimulating factor 1 (macrophage) 2.11932
PDHX pyruvate dehydrogenase complex, component X 2.11647
HIP1R huntingtin interacting protein 1 related 2.11591
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 2.11571
SERGEF secretion regulating guanine nucleotide exchange factor 2.11189
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 2.11146
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.11038
ZXDB zinc finger, X-linked, duplicated B 2.10956
PCOLCE2 procollagen C-endopeptidase enhancer 2 2.10951
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 2.1088
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) 2.10773
PDCD6 programmed cell death 6 2.10706
KRT33B keratin 33B, type I 2.10639
TDRD3 tudor domain containing 3 2.10604
SYT5 synaptotagmin V 2.10593
KLK14 kallikrein-related peptidase 14 2.10532
DIO3 deiodinase, iodothyronine, type III 2.10524
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) 2.10518
PCDHB6 protocadherin beta 6 2.10495
ETV2 ets variant 2 2.10489
MTMR10 myotubularin related protein 10 2.10269
DPH5 diphthamide biosynthesis 5 2.09975
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 2.09871
WDR91 WD repeat domain 91 2.09772
VAX2 ventral anterior homeobox 2 2.09769
ZNF385D zinc finger protein 385D 2.09754
APMAP adipocyte plasma membrane associated protein 2.09747
LINC02210-CRHR1 LINC02210-CRHR1 readthrough 2.097
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4 2.09625
POM121L2 POM121 transmembrane nucleoporin-like 2 2.09425
HRK harakiri, BCL2 interacting protein 2.09313
RANBP1 RAN binding protein 1 2.09282
TNNT2 troponin T type 2 (cardiac) 2.09228
IKZF2 IKAROS family zinc finger 2 (Helios) 2.09204
LRRC31 leucine rich repeat containing 31 2.09154
TMEM38B transmembrane protein 38B 2.09008
PSD4 pleckstrin and Sec7 domain containing 4 2.08932
GUCA2B guanylate cyclase activator 2B (uroguanylin) 2.08928
MAP1S microtubule-associated protein 1S 2.089
TMEM101 transmembrane protein 101 2.08895
NANOS1 nanos homolog 1 (Drosophila) 2.0889
HCRT hypocretin (orexin) neuropeptide precursor 2.08826
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 2.08769
FAIM2 Fas apoptotic inhibitory molecule 2 2.08461
XCL1 chemokine (C motif) ligand 1 2.08332
TAS2R4 taste receptor, type 2, member 4 2.08217
NPPB natriuretic peptide B 2.08118
MED24 mediator complex subunit 24 2.08078
EYA1 EYA transcriptional coactivator and phosphatase 1 2.0806
RPRM reprimo, TP53 dependent G2 arrest mediator candidate 2.08028
IL26 interleukin 26 2.07969
TUBA8 tubulin, alpha 8 2.0792
FAM50B family with sequence similarity 50, member B 2.07889
ZNF571 zinc finger protein 571 2.0788
LINS1 lines homolog 1 2.07877
CFHR3 complement factor H-related 3 2.07836
CD247 CD247 molecule 2.07729
ENPEP glutamyl aminopeptidase (aminopeptidase A) 2.0771
RPUSD2 RNA pseudouridylate synthase domain containing 2 2.07694
FGR FGR proto-oncogene, Src family tyrosine kinase 2.07686
PPAN-P2RY11 PPAN-P2RY11 readthrough 2.07632
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 2.07527
CD2AP CD2-associated protein 2.07525
TRIM46 tripartite motif containing 46 2.07379
NECTIN1 nectin cell adhesion molecule 1 2.0722
PTPRJ protein tyrosine phosphatase, receptor type, J 2.07023
NUCB1 nucleobindin 1 2.06928
MUC6 mucin 6, oligomeric mucus/gel-forming 2.06867
PCDHA2 protocadherin alpha 2 2.06844
RAB17 RAB17, member RAS oncogene family 2.06809
WSCD1 WSC domain containing 1 2.06683
KRT38 keratin 38, type I 2.06668
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 2.06619
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 2.06614
CASC3 cancer susceptibility candidate 3 2.06487
CDK5 cyclin-dependent kinase 5 2.06355
CIB2 calcium and integrin binding family member 2 2.06234
NEUROG1 neurogenin 1 2.06219
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 2.06155
FAM120C family with sequence similarity 120C 2.06138
PNMA2 paraneoplastic Ma antigen 2 2.05965
PLAAT2 phospholipase A and acyltransferase 2 2.05909
AKAP4 A kinase (PRKA) anchor protein 4 2.05847
SNX3 sorting nexin 3 2.05779
RAPSN receptor-associated protein of the synapse 2.0575
ZNF688 zinc finger protein 688 2.05717
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 2.05637
KRT1 keratin 1, type II 2.05618
AVPR2 arginine vasopressin receptor 2 2.05567
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 2.05464
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) 2.0544
ADRB1 adrenoceptor beta 1 2.05431
BFSP2 beaded filament structural protein 2, phakinin 2.05346
KYAT1 kynurenine aminotransferase 1 2.05325
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) 2.05325
CSN1S1 casein alpha s1 2.05224
IKZF3 IKAROS family zinc finger 3 (Aiolos) 2.05189
ARR3 arrestin 3, retinal (X-arrestin) 2.05178
LLGL2 lethal giant larvae homolog 2 (Drosophila) 2.0508
LUC7L LUC7-like (S. cerevisiae) 2.05066
PAX9 paired box 9 2.05008
TYR tyrosinase 2.04949
SIX2 SIX homeobox 2 2.0468
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 2.04646
TEX2 testis expressed 2 2.04574
HDAC6 histone deacetylase 6 2.04488
PTDSS2 phosphatidylserine synthase 2 2.04479
ECSIT ECSIT signalling integrator 2.04449
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 2.04448
ERN1 endoplasmic reticulum to nucleus signaling 1 2.04418
CPLX3 complexin 3 2.04319
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 2.04173
MRAS muscle RAS oncogene homolog 2.04171
SERINC1 serine incorporator 1 2.04056
ACTC1 actin, alpha, cardiac muscle 1 2.04013
TMC5 transmembrane channel-like 5 2.03875
PALM paralemmin 2.03755
SCN2B sodium channel, voltage gated, type II beta subunit 2.03675
PPP1R37 protein phosphatase 1, regulatory subunit 37 2.03571
GPR32 G protein-coupled receptor 32 2.03548
RNASE6 ribonuclease, RNase A family, k6 2.03435
FKBPL FK506 binding protein like 2.03357
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 2.03278
LMX1B LIM homeobox transcription factor 1, beta 2.03262
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 2.03192
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.03091
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 2.03066
IQSEC3 IQ motif and Sec7 domain 3 2.03011
OXCT2 3-oxoacid CoA transferase 2 2.02923
PSG11 pregnancy specific beta-1-glycoprotein 11 2.02902
ZDHHC24 zinc finger, DHHC-type containing 24 2.02879
RANGAP1 Ran GTPase activating protein 1 2.02706
FGF6 fibroblast growth factor 6 2.02661
HOXD12 homeobox D12 2.02628
BOLA1 bolA family member 1 2.02527
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 2.02408
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase 2.0235
NKX3-1 NK3 homeobox 1 2.02304
FAM117A family with sequence similarity 117, member A 2.02286
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 2.0218
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 2.0214
GHSR growth hormone secretagogue receptor 2.01994
FRRS1L ferric-chelate reductase 1-like 2.0194
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 2.01898
PRR5 proline rich 5 (renal) 2.01894
ERO1B endoplasmic reticulum oxidoreductase 1 beta 2.01767
JAKMIP2 janus kinase and microtubule interacting protein 2 2.01746
PCDHGA9 protocadherin gamma subfamily A, 9 2.01739
F2RL2 coagulation factor II (thrombin) receptor-like 2 2.01722
PRDM9 PR domain containing 9 2.01584
MYL4 myosin, light chain 4, alkali; atrial, embryonic 2.01448
BORCS6 BLOC-1 related complex subunit 6 2.01418
OPRD1 opioid receptor, delta 1 2.01368
CNGA1 cyclic nucleotide gated channel alpha 1 2.01352
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 2.013
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 2.01258
RTL10 retrotransposon Gag like 10 2.01241
NMD3 NMD3 ribosome export adaptor 2.01236
ACVR2B activin A receptor, type IIB 2.01226
RARA retinoic acid receptor, alpha 2.01172
GSTM4 glutathione S-transferase mu 4 2.01111
GRIA4 glutamate receptor, ionotropic, AMPA 4 2.01104
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2 2.01085
GJA8 gap junction protein, alpha 8, 50kDa 2.01035
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 2.01
HOXD10 homeobox D10 2.00993
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 2.00982
STC2 stanniocalcin 2 2.00961
KLHDC2 kelch domain containing 2 2.00954
COQ4 coenzyme Q4 2.00789
CALY calcyon neuron-specific vesicular protein 2.00771
TRO trophinin 2.00442
SEPTIN5 septin 5 2.00401
PEDS1 plasmanylethanolamine desaturase 1 2.00394
KRTAP1-1 keratin associated protein 1-1 2.00338
ABHD14A abhydrolase domain containing 14A 2.00308
ULBP1 UL16 binding protein 1 2.00304
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 2.00171
KANK2 KN motif and ankyrin repeat domains 2 2.00109
GAST gastrin 2.00085
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 2.00017
NAGLU N-acetylglucosaminidase, alpha 2.00001

decreased expression

Symbol Name Standardized Value
ANXA3 annexin A3 -6.91186
LOC124907782 dual specificity protein phosphatase 22 -5.54564
MSMO1 methylsterol monooxygenase 1 -4.72114
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.90847
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -3.89117
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -3.81157
TMA7 translation machinery associated 7 homolog (S. cerevisiae) -3.78263
HAUS2 HAUS augmin-like complex, subunit 2 -3.64247
STXBP2 syntaxin binding protein 2 -3.61175
HSPA1A heat shock 70kDa protein 1A -3.47442
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -3.47385
MKNK2 MAP kinase interacting serine/threonine kinase 2 -3.46424
PRR11 proline rich 11 -3.38968
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.38896
SQLE squalene epoxidase -3.35058
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -3.29865
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) -3.27976
NGRN neugrin, neurite outgrowth associated -3.22551
VAT1 vesicle amine transport 1 -3.22291
CRYZ crystallin, zeta (quinone reductase) -3.16464
AEBP1 AE binding protein 1 -3.14819
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 -3.11409
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides -3.11098
IGFBP7 insulin-like growth factor binding protein 7 -3.0591
PDLIM1 PDZ and LIM domain 1 -3.01307
GNG5 guanine nucleotide binding protein (G protein), gamma 5 -3.0063
DENND3 DENN/MADD domain containing 3 -3.00603
NUAK2 NUAK family, SNF1-like kinase, 2 -2.96284
GPX2 glutathione peroxidase 2 -2.89625
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -2.8483
PTK6 protein tyrosine kinase 6 -2.83739
TAOK1 TAO kinase 1 -2.81763
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -2.79238
THSD1 thrombospondin, type I, domain containing 1 -2.71236
ADIPOR2 adiponectin receptor 2 -2.70848
CRYBG3 beta-gamma crystallin domain containing 3 -2.69043
COQ8A coenzyme Q8A -2.66656
UBE2A ubiquitin-conjugating enzyme E2A -2.66343
TOMM34 translocase of outer mitochondrial membrane 34 -2.64765
QRICH1 glutamine-rich 1 -2.64377
DVL3 dishevelled segment polarity protein 3 -2.64183
ALPK1 alpha-kinase 1 -2.63893
THBS4 thrombospondin 4 -2.62857
TTPAL tocopherol (alpha) transfer protein-like -2.60547
AP1G1 adaptor-related protein complex 1, gamma 1 subunit -2.60527
LMCD1 LIM and cysteine-rich domains 1 -2.60496
LYRM1 LYR motif containing 1 -2.60028
GOLT1B golgi transport 1B -2.59545
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein -2.58959
TENT2 terminal nucleotidyltransferase 2 -2.58898
ADGRA3 adhesion G protein-coupled receptor A3 -2.58532
FAM111A family with sequence similarity 111, member A -2.57845
TSPAN31 tetraspanin 31 -2.57095
GLTP glycolipid transfer protein -2.5643
ABHD18 abhydrolase domain containing 18 -2.55792
EI24 etoposide induced 2.4 -2.5469
PODNL1 podocan-like 1 -2.5454
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 -2.54076
GPX3 glutathione peroxidase 3 -2.54019
CCP110 centriolar coiled coil protein 110kDa -2.53761
CD24 CD24 molecule -2.53336
LGALSL lectin, galactoside-binding-like -2.52804
ADAM17 ADAM metallopeptidase domain 17 -2.52311
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.52185
LMAN2L lectin, mannose-binding 2-like -2.50856
TGFB1I1 transforming growth factor beta 1 induced transcript 1 -2.5072
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -2.49575
ISOC1 isochorismatase domain containing 1 -2.49421
FNBP1L formin binding protein 1-like -2.48264
NUP93 nucleoporin 93kDa -2.46297
HMGA2 high mobility group AT-hook 2 -2.45964
DUOX1 dual oxidase 1 -2.45825
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -2.4551
GFUS GDP-L-fucose synthase -2.45362
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 -2.44874
KLHL21 kelch-like family member 21 -2.44709
SCRIB scribbled planar cell polarity protein -2.43789
SMN2 survival of motor neuron 2, centromeric -2.43018
ZBED2 zinc finger, BED-type containing 2 -2.42875
SRPRB signal recognition particle receptor, B subunit -2.4114
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 -2.38555
IQCB1 IQ motif containing B1 -2.37501
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -2.37497
MFSD1 major facilitator superfamily domain containing 1 -2.37051
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -2.3691
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa -2.3548
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -2.33112
PDPN podoplanin -2.32795
NBEAL2 neurobeachin-like 2 -2.32628
ATP5F1E ATP synthase F1 subunit epsilon -2.31878
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -2.31809
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -2.3093
COMP cartilage oligomeric matrix protein -2.30683
WRN Werner syndrome, RecQ helicase-like -2.30644
NID2 nidogen 2 (osteonidogen) -2.30567
SNRPF small nuclear ribonucleoprotein polypeptide F -2.30125
TOMM6 translocase of outer mitochondrial membrane 6 homolog (yeast) -2.29954
SNX1 sorting nexin 1 -2.2958
CCN2 cellular communication network factor 2 -2.28404
TFCP2L1 transcription factor CP2-like 1 -2.28009
TMUB2 transmembrane and ubiquitin-like domain containing 2 -2.27328
GPSM2 G-protein signaling modulator 2 -2.26579
CTSD cathepsin D -2.2634
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -2.25943
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -2.24825
LAMB1 laminin, beta 1 -2.23649
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -2.23263
SH3TC1 SH3 domain and tetratricopeptide repeats 1 -2.23217
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.23186
INPP5D inositol polyphosphate-5-phosphatase, 145kDa -2.23128
UBAP2 ubiquitin associated protein 2 -2.22933
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -2.22591
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -2.22556
ZNF611 zinc finger protein 611 -2.22549
AAR2 AAR2 splicing factor homolog (S. cerevisiae) -2.22305
NOPCHAP1 NOP protein chaperone 1 -2.21505
NOD2 nucleotide-binding oligomerization domain containing 2 -2.2079
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.20393
ATP5ME ATP synthase membrane subunit e -2.20256
TFG TRK-fused gene -2.20136
COPG1 coatomer protein complex, subunit gamma 1 -2.2012
HCLS1 hematopoietic cell-specific Lyn substrate 1 -2.1992
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase -2.19125
COL17A1 collagen, type XVII, alpha 1 -2.17052
PTMA prothymosin, alpha -2.16798
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.16743
TRIP12 thyroid hormone receptor interactor 12 -2.16427
ARGLU1 arginine and glutamate rich 1 -2.16375
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.16114
ELOVL1 ELOVL fatty acid elongase 1 -2.152
RPS26 ribosomal protein S26 -2.1517
GRPEL1 GrpE-like 1, mitochondrial (E. coli) -2.15004
RPN1 ribophorin I -2.13718
EBNA1BP2 EBNA1 binding protein 2 -2.13592
JAM3 junctional adhesion molecule 3 -2.12974
COL10A1 collagen, type X, alpha 1 -2.12907
BABAM2 BRISC and BRCA1 A complex member 2 -2.12827
BBIP1 BBSome interacting protein 1 -2.12791
ZNF329 zinc finger protein 329 -2.12769
CETN3 centrin, EF-hand protein, 3 -2.12198
DGUOK deoxyguanosine kinase -2.1198
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like -2.11183
SNRPG small nuclear ribonucleoprotein polypeptide G -2.10419
TOB1 transducer of ERBB2, 1 -2.10393
ENOPH1 enolase-phosphatase 1 -2.10383
RABGGTB Rab geranylgeranyltransferase, beta subunit -2.10377
MINDY3 MINDY lysine 48 deubiquitinase 3 -2.10294
WDR3 WD repeat domain 3 -2.10067
C2CD2 C2 calcium-dependent domain containing 2 -2.10057
ORC6 origin recognition complex, subunit 6 -2.09851
GSTM3 glutathione S-transferase mu 3 (brain) -2.09784
SYBU syntabulin (syntaxin-interacting) -2.0964
TPPP3 tubulin polymerization-promoting protein family member 3 -2.09515
VIM vimentin -2.09074
LY75-CD302 LY75-CD302 readthrough -2.08642
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator -2.08313
ACACB acetyl-CoA carboxylase beta -2.07966
CDK4 cyclin-dependent kinase 4 -2.07929
CXCL2 chemokine (C-X-C motif) ligand 2 -2.07897
TDG thymine-DNA glycosylase -2.07187
COX6C cytochrome c oxidase subunit VIc -2.07019
IST1 increased sodium tolerance 1 homolog (yeast) -2.06953
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G -2.06744
PABPC3 poly(A) binding protein, cytoplasmic 3 -2.06205
UFM1 ubiquitin-fold modifier 1 -2.05892
TM9SF2 transmembrane 9 superfamily member 2 -2.05262
PRKX protein kinase, X-linked -2.04481
NME2 NME/NM23 nucleoside diphosphate kinase 2 -2.04222
MRPL34 mitochondrial ribosomal protein L34 -2.03886
AHNAK2 AHNAK nucleoprotein 2 -2.03813
PTBP1 polypyrimidine tract binding protein 1 -2.03613
MACIR macrophage immunometabolism regulator -2.03528
WDR43 WD repeat domain 43 -2.0336
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa -2.03091
SLC31A2 solute carrier family 31 (copper transporter), member 2 -2.02774
RLIG1 RNA 5'-phosphate and 3'-OH ligase 1 -2.02439
PRPS2 phosphoribosyl pyrophosphate synthetase 2 -2.02392
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa -2.02163
CAVIN1 caveolae associated protein 1 -2.02143
THBS2 thrombospondin 2 -2.01993
RAB5IF RAB5 interacting factor -2.01896
RPA3 replication protein A3, 14kDa -2.01381
KIN Kin17 DNA and RNA binding protein -2.01298
GAS6 growth arrest-specific 6 -2.0075
PRSS3 protease, serine, 3 -2.00584
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 -2.00471
WWP1 WW domain containing E3 ubiquitin protein ligase 1 -2.0046
NKIRAS2 NFKB inhibitor interacting Ras-like 2 -2.00208
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -2.00168
RBM22 RNA binding motif protein 22 -2.00116
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 -2.00107