| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMBA 99.96 um perturbation at 48 h in MCF10A (Carcinogenome) |
| Similar Terms | |
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109 genes differentially expressed following the CRCGN015_MCF10A_48H:H04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HBA1 | hemoglobin, alpha 1 | 4.48459 |
| WIF1 | WNT inhibitory factor 1 | 3.20639 |
| NOSIP | nitric oxide synthase interacting protein | 3.1429 |
| CCNA1 | cyclin A1 | 3.06935 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | 2.93806 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | 2.78604 |
| NUCB2 | nucleobindin 2 | 2.68602 |
| EVL | Enah/Vasp-like | 2.66242 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 2.59687 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 2.58673 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | 2.54355 |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha | 2.53206 |
| ATG7 | autophagy related 7 | 2.50978 |
| CHKB | choline kinase beta | 2.41261 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 2.38205 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | 2.38032 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 2.37607 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 2.36203 |
| GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa | 2.34269 |
| PDLIM1 | PDZ and LIM domain 1 | 2.29412 |
| SDF2L1 | stromal cell-derived factor 2-like 1 | 2.26466 |
| VEGFC | vascular endothelial growth factor C | 2.2623 |
| TSC22D1 | TSC22 domain family, member 1 | 2.23151 |
| KIF5A | kinesin family member 5A | 2.22813 |
| HMGXB3 | HMG box domain containing 3 | 2.22079 |
| DUSP6 | dual specificity phosphatase 6 | 2.20787 |
| MSH2 | mutS homolog 2 | 2.18857 |
| HIRA | histone cell cycle regulator | 2.18843 |
| FPGS | folylpolyglutamate synthase | 2.18108 |
| TMEM101 | transmembrane protein 101 | 2.16206 |
| ZNF692 | zinc finger protein 692 | 2.15987 |
| PDLIM4 | PDZ and LIM domain 4 | 2.15479 |
| SDC4 | syndecan 4 | 2.14269 |
| CERK | ceramide kinase | 2.14095 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 2.12462 |
| COL7A1 | collagen, type VII, alpha 1 | 2.11963 |
| ATP6V1E1 | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 | 2.11956 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 2.1187 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 2.08862 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 2.07842 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 | 2.0746 |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 | 2.06553 |
| HMGA2 | high mobility group AT-hook 2 | 2.0645 |
| TMPRSS6 | transmembrane protease, serine 6 | 2.05628 |
| GPR27 | G protein-coupled receptor 27 | 2.04057 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit | 2.03073 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 2.02713 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 2.02595 |
| POLR1E | polymerase (RNA) I polypeptide E, 53kDa | 2.02182 |
| LOC128966622 | putative protein N-methyltransferase FAM86B2 | 2.01807 |
| PPM1F | protein phosphatase, Mg2+/Mn2+ dependent, 1F | 2.01158 |
| ACTL6A | actin-like 6A | 2.0045 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDC20 | cell division cycle 20 | -5.68945 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -5.54295 |
| TMEM50A | transmembrane protein 50A | -4.73874 |
| WASHC4 | WASH complex subunit 4 | -4.56066 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | -3.71118 |
| MSMO1 | methylsterol monooxygenase 1 | -3.66248 |
| MUC13 | mucin 13, cell surface associated | -3.47532 |
| MVP | major vault protein | -3.18215 |
| ARHGAP4 | Rho GTPase activating protein 4 | -2.99407 |
| CRNN | cornulin | -2.91087 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -2.90843 |
| PLSCR4 | phospholipid scramblase 4 | -2.88812 |
| RAB8B | RAB8B, member RAS oncogene family | -2.87971 |
| ATG4A | autophagy related 4A, cysteine peptidase | -2.68256 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.65391 |
| GGPS1 | geranylgeranyl diphosphate synthase 1 | -2.61405 |
| PPCS | phosphopantothenoylcysteine synthetase | -2.59392 |
| PLK2 | polo-like kinase 2 | -2.56912 |
| AKTIP | AKT interacting protein | -2.55524 |
| NCK1 | NCK adaptor protein 1 | -2.52443 |
| ANKRD10 | ankyrin repeat domain 10 | -2.51101 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.45991 |
| TP53I3 | tumor protein p53 inducible protein 3 | -2.44691 |
| CD24 | CD24 molecule | -2.37417 |
| ALX1 | ALX homeobox 1 | -2.35975 |
| TRAM1 | translocation associated membrane protein 1 | -2.30278 |
| APPL2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 | -2.29579 |
| CCDC51 | coiled-coil domain containing 51 | -2.26554 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -2.26044 |
| NBEAL2 | neurobeachin-like 2 | -2.2585 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | -2.24491 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.22919 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -2.1738 |
| NXF2B | nuclear RNA export factor 2B | -2.16092 |
| RHOF | ras homolog family member F (in filopodia) | -2.15792 |
| PRR15L | proline rich 15-like | -2.1559 |
| TMEM255A | transmembrane protein 255A | -2.15549 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | -2.1543 |
| DOK4 | docking protein 4 | -2.15211 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -2.12286 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | -2.11996 |
| VIL1 | villin 1 | -2.11706 |
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 | -2.11609 |
| RIOK3 | RIO kinase 3 | -2.10991 |
| RBM34 | RNA binding motif protein 34 | -2.10317 |
| CRY1 | cryptochrome circadian clock 1 | -2.10225 |
| SLURP1 | secreted LY6/PLAUR domain containing 1 | -2.08144 |
| FASTKD5 | FAST kinase domains 5 | -2.07404 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -2.06201 |
| HSPB8 | heat shock 22kDa protein 8 | -2.04983 |
| CALML4 | calmodulin-like 4 | -2.04451 |
| VPS4A | vacuolar protein sorting 4 homolog A (S. cerevisiae) | -2.04239 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | -2.03596 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | -2.02002 |
| RRAGC | Ras-related GTP binding C | -2.01499 |
| REG1A | regenerating islet-derived 1 alpha | -2.01393 |
| ILK | integrin-linked kinase | -2.00517 |
