CRCGN015_MCF10A_48H:H06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMBA 11.11 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

12 genes differentially expressed following the CRCGN015_MCF10A_48H:H06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCR4 chemokine (C-X-C motif) receptor 4 2.30771
CDPF1 cysteine-rich, DPF motif domain containing 1 2.14447
SLC31A1 solute carrier family 31 (copper transporter), member 1 2.14203
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.12391
DHDDS dehydrodolichyl diphosphate synthase 2.09195
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 2.07973
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.0733

decreased expression

Symbol Name Standardized Value
HSPA8 heat shock 70kDa protein 8 -4.17642
ZBTB35 zinc finger and BTB domain containing 35 -3.01086
MT2A metallothionein 2A -2.75966
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -2.13717
HPRT1 hypoxanthine phosphoribosyltransferase 1 -2.0735