CRCGN015_MCF10A_48H:H07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4-aminostilbene 100.39 um perturbation at 48 h in MCF10A (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

75 genes differentially expressed following the CRCGN015_MCF10A_48H:H07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 3.84819
WIF1 WNT inhibitory factor 1 3.11105
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 3.04018
BIRC3 baculoviral IAP repeat containing 3 3.02212
IL7 interleukin 7 2.51088
LDAF1 lipid droplet assembly factor 1 2.43435
SCARA3 scavenger receptor class A, member 3 2.40486
H2BC5 H2B clustered histone 5 2.34684
COPG1 coatomer protein complex, subunit gamma 1 2.31031
H2AC6 H2A clustered histone 6 2.30011
TMEM50A transmembrane protein 50A 2.28984
KIAA0319L KIAA0319-like 2.24868
RBBP5 retinoblastoma binding protein 5 2.24211
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.20093
TLR3 toll-like receptor 3 2.14374
SLC30A1 solute carrier family 30 (zinc transporter), member 1 2.14327
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.13907
GPAA1 glycosylphosphatidylinositol anchor attachment 1 2.12835
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 2.12634
RAB15 RAB15, member RAS oncogene family 2.12488
KEAP1 kelch-like ECH-associated protein 1 2.09501
GJA4 gap junction protein, alpha 4, 37kDa 2.08471
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase 2.07766
CLU clusterin 2.05344
NUCB2 nucleobindin 2 2.02983
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 2.02376

decreased expression

Symbol Name Standardized Value
ANXA3 annexin A3 -6.27135
GNAS GNAS complex locus -3.89817
MELK maternal embryonic leucine zipper kinase -2.98858
TRIP13 thyroid hormone receptor interactor 13 -2.93199
RUVBL1 RuvB-like AAA ATPase 1 -2.83926
CDC25B cell division cycle 25B -2.71576
LDHB lactate dehydrogenase B -2.65095
RPLP2 ribosomal protein, large, P2 -2.63496
RPL38 ribosomal protein L38 -2.5789
NUP85 nucleoporin 85kDa -2.49263
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor -2.4824
PRELID3B PRELI domain containing 3B -2.46517
CDC20 cell division cycle 20 -2.45245
ACTG1 actin gamma 1 -2.41718
LDHA lactate dehydrogenase A -2.41261
ZBTB35 zinc finger and BTB domain containing 35 -2.40768
TUBA1B tubulin, alpha 1b -2.40738
TUBA1C tubulin, alpha 1c -2.38143
PTCD3 pentatricopeptide repeat domain 3 -2.36328
ATP5F1E ATP synthase F1 subunit epsilon -2.35103
CALM2 calmodulin 2 (phosphorylase kinase, delta) -2.32384
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.30968
MKNK1 MAP kinase interacting serine/threonine kinase 1 -2.30659
TACC3 transforming, acidic coiled-coil containing protein 3 -2.29069
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) -2.2906
PLK1 polo-like kinase 1 -2.26068
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -2.23728
ATP5F1A ATP synthase F1 subunit alpha -2.23274
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.23104
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 -2.20327
WDR12 WD repeat domain 12 -2.19733
NELFCD negative elongation factor complex member C/D -2.18564
PSRC1 proline/serine-rich coiled-coil 1 -2.15369
BLMH bleomycin hydrolase -2.15048
NCLN nicalin -2.12346
MRPS7 mitochondrial ribosomal protein S7 -2.11825
CNBP CCHC-type zinc finger, nucleic acid binding protein -2.11801
RPL4 ribosomal protein L4 -2.10096
PMPCA peptidase (mitochondrial processing) alpha -2.10009
RPL22 ribosomal protein L22 -2.08908
RPL35 ribosomal protein L35 -2.08356
MRPL12 mitochondrial ribosomal protein L12 -2.08029
NACA nascent polypeptide-associated complex alpha subunit -2.06694
WDR18 WD repeat domain 18 -2.05653
GPHN gephyrin -2.04261
KRT75 keratin 75, type II -2.03514
CLTB clathrin, light chain B -2.02955
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 -2.02232
MIS18A MIS18 kinetochore protein A -2.01846