CRCGN015_MCF10A_48H:H10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description maleic hydrazide 99.3 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN015_MCF10A_48H:H10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ANO10 anoctamin 10 3.16672
CCP110 centriolar coiled coil protein 110kDa 2.79511
FPGS folylpolyglutamate synthase 2.65544
PDIA5 protein disulfide isomerase family A, member 5 2.54339
PCM1 pericentriolar material 1 2.43633
GUF1 GUF1 GTPase homolog (S. cerevisiae) 2.09914

decreased expression

Symbol Name Standardized Value
RND3 Rho family GTPase 3 -2.89136
PLS1 plastin 1 -2.7009
GRB7 growth factor receptor-bound protein 7 -2.40673
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.36404
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -2.16703
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -2.08036
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.04534
NHLH1 nescient helix loop helix 1 -2.00344