CRCGN015_MCF10A_48H:H12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description maleic hydrazide 11.03 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN015_MCF10A_48H:H12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 2.32904
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.07596

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -4.55826
VIM vimentin -3.6316
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.50345
S100A8 S100 calcium binding protein A8 -3.49957
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.90334
CCNB1 cyclin B1 -2.69197
RND3 Rho family GTPase 3 -2.4266
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 -2.19243
PDLIM1 PDZ and LIM domain 1 -2.16679
PLK1 polo-like kinase 1 -2.13729
GRB7 growth factor receptor-bound protein 7 -2.11915
RGL4 ral guanine nucleotide dissociation stimulator-like 4 -2.1093
NR1H4 nuclear receptor subfamily 1, group H, member 4 -2.08146
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 -2.01924
TM9SF3 transmembrane 9 superfamily member 3 -2.01477