CRCGN015_MCF10A_48H:H14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methyl methacrylate 32.81 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

33 genes differentially expressed following the CRCGN015_MCF10A_48H:H14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 5.09829
CHMP6 charged multivesicular body protein 6 4.24319
FPGS folylpolyglutamate synthase 4.22764
MAP2K5 mitogen-activated protein kinase kinase 5 3.07977
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.87763
CDK9 cyclin-dependent kinase 9 2.85091
SNX11 sorting nexin 11 2.78745
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.39187
MTA2 metastasis associated 1 family, member 2 2.28224
PNPO pyridoxamine 5'-phosphate oxidase 2.21737
URM1 ubiquitin related modifier 1 2.16676
SCARA3 scavenger receptor class A, member 3 2.16151
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2.08343
BTBD1 BTB (POZ) domain containing 1 2.08046
IGFALS insulin-like growth factor binding protein, acid labile subunit 2.07178
GLI1 GLI family zinc finger 1 2.05899
SMG6 SMG6 nonsense mediated mRNA decay factor 2.05515
EPN2 epsin 2 2.04996
TMEM14A transmembrane protein 14A 2.04332

decreased expression

Symbol Name Standardized Value
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.48538
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -3.70377
GNAS GNAS complex locus -3.54974
CALM2 calmodulin 2 (phosphorylase kinase, delta) -2.7193
ATP5F1E ATP synthase F1 subunit epsilon -2.60106
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -2.48399
TMEM255A transmembrane protein 255A -2.42781
RPN2 ribophorin II -2.36429
SF3B2 splicing factor 3b, subunit 2, 145kDa -2.25817
TUBA1B tubulin, alpha 1b -2.15552
EMC7 ER membrane protein complex subunit 7 -2.14858
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -2.1123
NELFCD negative elongation factor complex member C/D -2.08711
PCBP1 poly(rC) binding protein 1 -2.03633