CRCGN015_MCF10A_48H:H15 Gene Set
Genes
48 genes differentially expressed following the CRCGN015_MCF10A_48H:H15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
EAPP
|
E2F-associated phosphoprotein
|
4.0033
|
|
TLR4
|
toll-like receptor 4
|
3.76621
|
|
MAP2K5
|
mitogen-activated protein kinase kinase 5
|
3.33609
|
|
HYOU1
|
hypoxia up-regulated 1
|
3.07296
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
2.8131
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.77321
|
|
CHEK2
|
checkpoint kinase 2
|
2.72662
|
|
KBTBD11
|
kelch repeat and BTB (POZ) domain containing 11
|
2.7237
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
2.66267
|
|
TLCD3A
|
TLC domain containing 3A
|
2.53946
|
|
KCTD5
|
potassium channel tetramerization domain containing 5
|
2.4238
|
|
LRRC41
|
leucine rich repeat containing 41
|
2.37266
|
|
EVL
|
Enah/Vasp-like
|
2.26004
|
|
TUBA1B
|
tubulin, alpha 1b
|
2.24585
|
|
H2AX
|
H2A.X variant histone
|
2.23738
|
|
ANAPC1
|
anaphase promoting complex subunit 1
|
2.20842
|
|
PELI2
|
pellino E3 ubiquitin protein ligase family member 2
|
2.20641
|
|
TMEM135
|
transmembrane protein 135
|
2.16652
|
|
KLHL26
|
kelch-like family member 26
|
2.16221
|
|
SETMAR
|
SET domain and mariner transposase fusion gene
|
2.13798
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
2.1161
|
|
TRAM2
|
translocation associated membrane protein 2
|
2.0916
|
|
EXT2
|
exostosin glycosyltransferase 2
|
2.06819
|
|
DBNDD1
|
dysbindin (dystrobrevin binding protein 1) domain containing 1
|
2.06418
|
|
EIF1AY
|
eukaryotic translation initiation factor 1A, Y-linked
|
2.05103
|
|
USP7
|
ubiquitin specific peptidase 7 (herpes virus-associated)
|
2.00379
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
2.00022
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PLS1
|
plastin 1
|
-5.56581
|
|
MT2A
|
metallothionein 2A
|
-4.72315
|
|
PSMD10
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
|
-3.51081
|
|
VIM
|
vimentin
|
-3.05434
|
|
KRT14
|
keratin 14, type I
|
-2.89981
|
|
KRT7
|
keratin 7, type II
|
-2.83318
|
|
WBP1L
|
WW domain binding protein 1-like
|
-2.70297
|
|
ATG3
|
autophagy related 3
|
-2.61463
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.58997
|
|
RPN1
|
ribophorin I
|
-2.50872
|
|
PTTG1IP
|
pituitary tumor-transforming 1 interacting protein
|
-2.29656
|
|
DNAJC12
|
DnaJ (Hsp40) homolog, subfamily C, member 12
|
-2.27499
|
|
GFPT1
|
glutamine--fructose-6-phosphate transaminase 1
|
-2.27177
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.19134
|
|
SLC35A5
|
solute carrier family 35, member A5
|
-2.11758
|
|
PLK2
|
polo-like kinase 2
|
-2.08955
|
|
IRS1
|
insulin receptor substrate 1
|
-2.0732
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.04776
|
|
ELOVL1
|
ELOVL fatty acid elongase 1
|
-2.02571
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.01631
|
|
CSRP2
|
cysteine and glycine-rich protein 2
|
-2.01225
|
