CRCGN015_MCF10A_48H:H16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-(chloromethyl)pyridine.hcl 99.45 um perturbation at 48 h in MCF10A (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

33 genes differentially expressed following the CRCGN015_MCF10A_48H:H16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
LAGE3 L antigen family, member 3 3.12408
GRWD1 glutamate-rich WD repeat containing 1 2.85985
LOC122526780 uncharacterized LOC122526780 2.69436
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.61134
FGFR4 fibroblast growth factor receptor 4 2.47587
FPGS folylpolyglutamate synthase 2.40861
HMGA2 high mobility group AT-hook 2 2.36265
HLTF helicase-like transcription factor 2.3487
POLR1G RNA polymerase I subunit G 2.31565
LUC7L2 LUC7-like 2 (S. cerevisiae) 2.29085
KIFBP kinesin family binding protein 2.20411
CCDC85B coiled-coil domain containing 85B 2.18545
PUS7 pseudouridylate synthase 7 (putative) 2.13584
TMEM50A transmembrane protein 50A 2.12598
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.05619

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -4.94437
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 -4.31556
INPP1 inositol polyphosphate-1-phosphatase -4.17252
KRT14 keratin 14, type I -3.30736
LOC124907782 dual specificity protein phosphatase 22 -2.63177
GABARAPL2 GABA(A) receptor-associated protein-like 2 -2.4562
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -2.30439
DSG3 desmoglein 3 -2.25687
ANXA3 annexin A3 -2.2115
CDPF1 cysteine-rich, DPF motif domain containing 1 -2.15438
CCDC186 coiled-coil domain containing 186 -2.12159
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.11533
PCDHB16 protocadherin beta 16 -2.08809
MFSD6 major facilitator superfamily domain containing 6 -2.08489
ALDOC aldolase C, fructose-bisphosphate -2.08479
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -2.06526
SLC25A46 solute carrier family 25, member 46 -2.05059
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -2.03452