CRCGN015_MCF10A_48H:H18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-(chloromethyl)pyridine.hcl 11.05 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN015_MCF10A_48H:H18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 3.21646
PRKCQ protein kinase C, theta 2.91898
AMDHD2 amidohydrolase domain containing 2 2.61688
CASP10 caspase 10, apoptosis-related cysteine peptidase 2.51634
SNAP25 synaptosomal-associated protein, 25kDa 2.37615
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 2.27451
EXOSC4 exosome component 4 2.11545
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 2.09628
AK6 adenylate kinase 6 2.01984

decreased expression

Symbol Name Standardized Value
DERA deoxyribose-phosphate aldolase (putative) -3.55018
CDC20 cell division cycle 20 -3.49924
SLC35F2 solute carrier family 35, member F2 -2.90704
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.751
VIM vimentin -2.56964
S100A8 S100 calcium binding protein A8 -2.53781
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -2.31552
TTC17 tetratricopeptide repeat domain 17 -2.21672
IGFBP7 insulin-like growth factor binding protein 7 -2.14077
ELOVL1 ELOVL fatty acid elongase 1 -2.12964