CRCGN015_MCF10A_48H:H20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description estradiol 34.78 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

9 genes differentially expressed following the CRCGN015_MCF10A_48H:H20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.731
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.67188
KDM5A lysine (K)-specific demethylase 5A 2.9112
FZD1 frizzled class receptor 1 2.41259
SIRT3 sirtuin 3 2.02982
MAP2K5 mitogen-activated protein kinase kinase 5 2.02693

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -7.95753
NCK1 NCK adaptor protein 1 -3.7501
PLK2 polo-like kinase 2 -2.99547