CRCGN015_MCF10A_48H:I01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzyl-alcohol 99.96 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

38 genes differentially expressed following the CRCGN015_MCF10A_48H:I01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STIMATE STIM activating enhancer 5.7016
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 3.9649
CCP110 centriolar coiled coil protein 110kDa 3.65705
PRKCQ protein kinase C, theta 3.37112
ERMAP erythroblast membrane-associated protein (Scianna blood group) 2.8604
PNRC1 proline-rich nuclear receptor coactivator 1 2.8286
SIRT3 sirtuin 3 2.70772
PDF peptide deformylase (mitochondrial) 2.5458
NOSIP nitric oxide synthase interacting protein 2.52025
NEK4 NIMA-related kinase 4 2.4098
CEP57 centrosomal protein 57kDa 2.361
GCLC glutamate-cysteine ligase, catalytic subunit 2.30955
ZNF322 zinc finger protein 322 2.264
TOLLIP toll interacting protein 2.15175
NT5DC2 5'-nucleotidase domain containing 2 2.13705
FECH ferrochelatase 2.11102
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 2.09337
MLYCD malonyl-CoA decarboxylase 2.0884
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 2.0469
TMEM242 transmembrane protein 242 2.0366
GALNS galactosamine (N-acetyl)-6-sulfatase 2.01185
UBE4B ubiquitination factor E4B 2.00695
KLHL21 kelch-like family member 21 2.00115

decreased expression

Symbol Name Standardized Value
DHRS7 dehydrogenase/reductase (SDR family) member 7 -5.25175
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -4.56875
VIM vimentin -4.542
LRP10 low density lipoprotein receptor-related protein 10 -4.3958
REEP5 receptor accessory protein 5 -4.34192
KRT14 keratin 14, type I -2.73775
UBE2A ubiquitin-conjugating enzyme E2A -2.47915
CSRP2 cysteine and glycine-rich protein 2 -2.4633
IGFBP7 insulin-like growth factor binding protein 7 -2.40875
MORC4 MORC family CW-type zinc finger 4 -2.3553
MFAP2 microfibrillar-associated protein 2 -2.32905
KRT8 keratin 8, type II -2.2741
HEATR1 HEAT repeat containing 1 -2.1769
KRT7 keratin 7, type II -2.07375
ACTG2 actin, gamma 2, smooth muscle, enteric -2.05465