CRCGN015_MCF10A_48H:I03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzyl-alcohol 11.11 um perturbation at 48 h in MCF10A (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

53 genes differentially expressed following the CRCGN015_MCF10A_48H:I03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TIAM1 T-cell lymphoma invasion and metastasis 1 3.62231
TXNL4B thioredoxin-like 4B 2.83274
IL7 interleukin 7 2.4529
LTBP1 latent transforming growth factor beta binding protein 1 2.43209
R3HCC1L R3H domain and coiled-coil containing 1-like 2.377
CASP1 caspase 1, apoptosis-related cysteine peptidase 2.32947
BIRC3 baculoviral IAP repeat containing 3 2.30206
SLC30A1 solute carrier family 30 (zinc transporter), member 1 2.28002
MED17 mediator complex subunit 17 2.23735
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 2.22791
PRR5 proline rich 5 (renal) 2.19161
ANKRD49 ankyrin repeat domain 49 2.13622
SDHAF3 succinate dehydrogenase complex assembly factor 3 2.05233
QSER1 glutamine and serine rich 1 2.0502
RWDD3 RWD domain containing 3 2.04614
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 2.03957
TCF20 transcription factor 20 (AR1) 2.03562
BCL2L14 BCL2-like 14 (apoptosis facilitator) 2.02218
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa 2.00977
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa 2.00233

decreased expression

Symbol Name Standardized Value
ANXA3 annexin A3 -6.7057
CTSL cathepsin L -5.80164
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -5.2539
VIM vimentin -5.0
CCNB2 cyclin B2 -4.91609
IGFBP7 insulin-like growth factor binding protein 7 -4.44816
GNAS GNAS complex locus -4.41113
LDHB lactate dehydrogenase B -3.49229
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa -3.19745
NELFCD negative elongation factor complex member C/D -3.17894
VTI1B vesicle transport through interaction with t-SNAREs 1B -3.1673
ATP5F1E ATP synthase F1 subunit epsilon -3.15969
FN1 fibronectin 1 -3.09436
CALM2 calmodulin 2 (phosphorylase kinase, delta) -2.49908
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -2.33122
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -2.30304
RPN2 ribophorin II -2.28923
SNUPN snurportin 1 -2.27946
CD24 CD24 molecule -2.26911
HLA-A major histocompatibility complex, class I, A -2.26011
GNG5 guanine nucleotide binding protein (G protein), gamma 5 -2.21954
COPS5 COP9 signalosome subunit 5 -2.19574
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.19052
PGAP6 post-GPI attachment to proteins 6 -2.17301
LAMA5 laminin, alpha 5 -2.16389
PLA2G2D phospholipase A2, group IID -2.1135
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 -2.10823
FGD1 FYVE, RhoGEF and PH domain containing 1 -2.10616
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H -2.10546
BBOF1 basal body orientation factor 1 -2.09949
RTRAF RNA transcription, translation and transport factor -2.07979
XPA xeroderma pigmentosum, complementation group A -2.06842
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1 -2.03471