| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | monoethylhexylphthalate 11.22 um perturbation at 48 h in MCF10A (Carcinogenome) |
| Similar Terms | |
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54 genes differentially expressed following the CRCGN015_MCF10A_48H:I06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BAX | BCL2-associated X protein | 5.02665 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) | 4.21335 |
| ZW10 | zw10 kinetochore protein | 3.83955 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.64248 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | 2.86247 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 | 2.74545 |
| ARB2A | ARB2 cotranscriptional regulator A | 2.74185 |
| LMNB1 | lamin B1 | 2.4096 |
| RCC1 | regulator of chromosome condensation 1 | 2.40905 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.4076 |
| FLT3 | fms-related tyrosine kinase 3 | 2.4004 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | 2.38322 |
| NKAPD1 | NKAP domain containing 1 | 2.29035 |
| CRTC3 | CREB regulated transcription coactivator 3 | 2.28365 |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 | 2.24055 |
| APH1A | APH1A gamma secretase subunit | 2.23715 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.21805 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 2.19358 |
| GATAD2A | GATA zinc finger domain containing 2A | 2.17555 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C | 2.16055 |
| HIRA | histone cell cycle regulator | 2.1551 |
| ATP5F1A | ATP synthase F1 subunit alpha | 2.1445 |
| PHF10 | PHD finger protein 10 | 2.1041 |
| SRSF8 | serine/arginine-rich splicing factor 8 | 2.07675 |
| EXT2 | exostosin glycosyltransferase 2 | 2.04763 |
| EIF2D | eukaryotic translation initiation factor 2D | 2.0334 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -6.36295 |
| RPA3 | replication protein A3, 14kDa | -4.9541 |
| MT1X | metallothionein 1X | -3.29827 |
| BBOF1 | basal body orientation factor 1 | -3.0895 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.99205 |
| CSRP2 | cysteine and glycine-rich protein 2 | -2.91485 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -2.58177 |
| IRF9 | interferon regulatory factor 9 | -2.53705 |
| CD24 | CD24 molecule | -2.52684 |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | -2.5014 |
| BLVRB | biliverdin reductase B | -2.49665 |
| EMC3 | ER membrane protein complex subunit 3 | -2.48575 |
| PDLIM1 | PDZ and LIM domain 1 | -2.437 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -2.34355 |
| PLD2 | phospholipase D2 | -2.34165 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 | -2.3406 |
| VTI1B | vesicle transport through interaction with t-SNAREs 1B | -2.30535 |
| ALS2CL | ALS2 C-terminal like | -2.29965 |
| CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 | -2.22845 |
| MPHOSPH6 | M-phase phosphoprotein 6 | -2.21695 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | -2.1932 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -2.13485 |
| RND3 | Rho family GTPase 3 | -2.1033 |
| PSMB6 | proteasome (prosome, macropain) subunit, beta type, 6 | -2.0684 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -2.0255 |
| VAT1 | vesicle amine transport 1 | -2.02375 |
| COXFA4 | cytochrome c oxidase associated subunit FA4 | -2.0203 |
| ISG15 | ISG15 ubiquitin-like modifier | -2.0049 |
