CRCGN015_MCF10A_48H:I10 Gene Set
Genes
32 genes differentially expressed following the CRCGN015_MCF10A_48H:I10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
WIF1
|
WNT inhibitory factor 1
|
4.24709
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
2.99373
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
2.90786
|
|
STK10
|
serine/threonine kinase 10
|
2.61739
|
|
USP7
|
ubiquitin specific peptidase 7 (herpes virus-associated)
|
2.6027
|
|
SNX11
|
sorting nexin 11
|
2.57237
|
|
ZNF589
|
zinc finger protein 589
|
2.56969
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
2.3231
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.19673
|
|
CCNB2
|
cyclin B2
|
2.0648
|
|
DUSP6
|
dual specificity phosphatase 6
|
2.04815
|
|
TPST1
|
tyrosylprotein sulfotransferase 1
|
2.01731
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MSMO1
|
methylsterol monooxygenase 1
|
-7.10703
|
|
S100A8
|
S100 calcium binding protein A8
|
-5.49587
|
|
PLS1
|
plastin 1
|
-4.16097
|
|
PLK2
|
polo-like kinase 2
|
-3.67192
|
|
ELOVL6
|
ELOVL fatty acid elongase 6
|
-2.80985
|
|
SCYL3
|
SCY1-like 3 (S. cerevisiae)
|
-2.66577
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.37576
|
|
SLC2A6
|
solute carrier family 2 (facilitated glucose transporter), member 6
|
-2.35838
|
|
TNFSF10
|
tumor necrosis factor (ligand) superfamily, member 10
|
-2.34686
|
|
IGFBP7
|
insulin-like growth factor binding protein 7
|
-2.34644
|
|
P2RY6
|
pyrimidinergic receptor P2Y, G-protein coupled, 6
|
-2.28599
|
|
MT2A
|
metallothionein 2A
|
-2.24832
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
-2.22212
|
|
KIF13B
|
kinesin family member 13B
|
-2.16001
|
|
DDX60
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
|
-2.15521
|
|
OCLN
|
occludin
|
-2.0883
|
|
QSOX1
|
quiescin Q6 sulfhydryl oxidase 1
|
-2.08198
|
|
MAFF
|
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
|
-2.01463
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
-2.0112
|
|
COQ10B
|
coenzyme Q10 homolog B (S. cerevisiae)
|
-2.00354
|
