CRCGN015_MCF10A_48H:I11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description aroclor 1260 31.94 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

49 genes differentially expressed following the CRCGN015_MCF10A_48H:I11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 6.8107
KIFBP kinesin family binding protein 2.81411
EVL Enah/Vasp-like 2.58134
TIAM1 T-cell lymphoma invasion and metastasis 1 2.33938
TRIP6 thyroid hormone receptor interactor 6 2.3122
PCM1 pericentriolar material 1 2.2544
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 2.22874
HAVCR1 hepatitis A virus cellular receptor 1 2.18368
SLC26A2 solute carrier family 26 (anion exchanger), member 2 2.14047
TFG TRK-fused gene 2.12363
MRPL42 mitochondrial ribosomal protein L42 2.1223
TTK TTK protein kinase 2.11698
PDIA5 protein disulfide isomerase family A, member 5 2.08735
ZWILCH zwilch kinetochore protein 2.08361
CRTAP cartilage associated protein 2.04398

decreased expression

Symbol Name Standardized Value
PLK2 polo-like kinase 2 -3.92189
MSMO1 methylsterol monooxygenase 1 -3.91425
ENOPH1 enolase-phosphatase 1 -3.87573
MT2A metallothionein 2A -3.21771
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -2.76859
ERC2 ELKS/RAB6-interacting/CAST family member 2 -2.61421
LOC124907782 dual specificity protein phosphatase 22 -2.59146
KRT14 keratin 14, type I -2.37093
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -2.36122
ANXA9 annexin A9 -2.23659
TDRD12 tudor domain containing 12 -2.21002
CSRP2 cysteine and glycine-rich protein 2 -2.20224
BCL2L2 BCL2-like 2 -2.19536
NBEAL2 neurobeachin-like 2 -2.1532
KRT23 keratin 23, type I -2.13857
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -2.12831
PRODH2 proline dehydrogenase (oxidase) 2 -2.12674
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide -2.09199
EPS8L1 EPS8-like 1 -2.08022
CRABP2 cellular retinoic acid binding protein 2 -2.06111
FGA fibrinogen alpha chain -2.05773
ND5 NADH dehydrogenase subunit 5 -2.05393
PEG10 paternally expressed 10 -2.0471
POLH polymerase (DNA directed), eta -2.04533
GH1 growth hormone 1 -2.03366
PBX3 pre-B-cell leukemia homeobox 3 -2.03186
ARG2 arginase 2 -2.02558
INHBB inhibin, beta B -2.02363
CLCNKB chloride channel, voltage-sensitive Kb -2.02335
SPTBN2 spectrin, beta, non-erythrocytic 2 -2.02014
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) -2.01974
LIN7B lin-7 homolog B (C. elegans) -2.00565
ANGPTL8 angiopoietin like 8 -2.00219
CCDC106 coiled-coil domain containing 106 -2.00066