CRCGN015_MCF10A_48H:I15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description toluene diisocyanate 11.31 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN015_MCF10A_48H:I15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GRB10 growth factor receptor-bound protein 10 4.21193
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.20671
STK25 serine/threonine kinase 25 4.03731
MEF2C myocyte enhancer factor 2C 3.76674
MINDY1 MINDY lysine 48 deubiquitinase 1 3.50842
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 3.18365
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.4013
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 2.38857
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 2.2024
EFNB2 ephrin-B2 2.11336

decreased expression

Symbol Name Standardized Value
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -4.04927
TUBB6 tubulin, beta 6 class V -3.59028
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.48935
MT2A metallothionein 2A -3.45321
S100A8 S100 calcium binding protein A8 -3.19091
DCK deoxycytidine kinase -2.39794
COG2 component of oligomeric golgi complex 2 -2.21463
BEX3 brain expressed X-linked 3 -2.1479
NXT1 nuclear transport factor 2-like export factor 1 -2.09318
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.04073