CRCGN015_MCF10A_48H:I17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hc yellow 4 33.27 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

27 genes differentially expressed following the CRCGN015_MCF10A_48H:I17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CD320 CD320 molecule 2.77445
CCNA1 cyclin A1 2.67069
WIF1 WNT inhibitory factor 1 2.51713
CERK ceramide kinase 2.38533
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.37959
CASP10 caspase 10, apoptosis-related cysteine peptidase 2.32687
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.3134
BZW2 basic leucine zipper and W2 domains 2 2.20085
ANO10 anoctamin 10 2.19647
CDC25A cell division cycle 25A 2.16412
KDM5D lysine (K)-specific demethylase 5D 2.1511
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.11364
KIF15 kinesin family member 15 2.05853

decreased expression

Symbol Name Standardized Value
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -4.79761
SMC1A structural maintenance of chromosomes 1A -3.4714
DCK deoxycytidine kinase -3.43525
TRAPPC3 trafficking protein particle complex 3 -2.94103
PCCB propionyl CoA carboxylase, beta polypeptide -2.90072
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) -2.81856
PDLIM1 PDZ and LIM domain 1 -2.69177
KDM5C lysine (K)-specific demethylase 5C -2.52413
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.44964
MT2A metallothionein 2A -2.15457
CASP7 caspase 7, apoptosis-related cysteine peptidase -2.04002
ATG4A autophagy related 4A, cysteine peptidase -2.03325
LOC124905557 eukaryotic translation initiation factor 1A, X-chromosomal -2.02525
NFIL3 nuclear factor, interleukin 3 regulated -2.00727