CRCGN015_MCF10A_48H:I18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hc yellow 4 11.09 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN015_MCF10A_48H:I18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 5.02977
CCDC92 coiled-coil domain containing 92 4.74437
PPARG peroxisome proliferator-activated receptor gamma 4.70073
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.67227
PECR peroxisomal trans-2-enoyl-CoA reductase 2.4668
PHC2 polyhomeotic homolog 2 (Drosophila) 2.27019
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 2.18612
BCL3 B-cell CLL/lymphoma 3 2.12326
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.06748
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.01989

decreased expression

Symbol Name Standardized Value
CSRP2 cysteine and glycine-rich protein 2 -3.40909
SORBS3 sorbin and SH3 domain containing 3 -3.2772
S100A8 S100 calcium binding protein A8 -2.75518
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) -2.50042
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog -2.22172
VIM vimentin -2.21264
FASTKD5 FAST kinase domains 5 -2.00885