CRCGN015_MCF10A_48H:I20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description thiotepa 32.96 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN015_MCF10A_48H:I20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CBR3 carbonyl reductase 3 2.891
MICALL1 MICAL-like 1 2.31722
MAP2K5 mitogen-activated protein kinase kinase 5 2.31181
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 2.23347
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.1947
SNX11 sorting nexin 11 2.17272
PCM1 pericentriolar material 1 2.13099
DHDDS dehydrodolichyl diphosphate synthase 2.08222
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 2.02152

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -4.68499
PCCB propionyl CoA carboxylase, beta polypeptide -4.27632
CSRP2 cysteine and glycine-rich protein 2 -2.63724
CD24 CD24 molecule -2.45484
VIM vimentin -2.21755
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa -2.00755