CRCGN015_MCF10A_48H:I21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description thiotepa 10.99 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

11 genes differentially expressed following the CRCGN015_MCF10A_48H:I21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
VAV3 vav 3 guanine nucleotide exchange factor 4.25663
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.78931
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 2.74086
TSEN2 TSEN2 tRNA splicing endonuclease subunit 2.3561
PCM1 pericentriolar material 1 2.17383

decreased expression

Symbol Name Standardized Value
DSG2 desmoglein 2 -4.76804
FOXJ3 forkhead box J3 -3.78568
EED embryonic ectoderm development -2.47959
ACKR3 atypical chemokine receptor 3 -2.03814
CIAO2B cytosolic iron-sulfur assembly component 2B -2.01656
ZSCAN18 zinc finger and SCAN domain containing 18 -2.01352