CRCGN015_MCF10A_48H:I23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tryptophan 33.66 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN015_MCF10A_48H:I23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
COQ8A coenzyme Q8A 3.92057
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 3.41307
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.40899
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.299
BMP4 bone morphogenetic protein 4 2.44052
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 2.43905
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 2.1926
SNX11 sorting nexin 11 2.10962
IPO13 importin 13 2.08096
IER3 immediate early response 3 2.03614
TSEN2 TSEN2 tRNA splicing endonuclease subunit 2.00461

decreased expression

Symbol Name Standardized Value
VIM vimentin -4.43337
IGFBP7 insulin-like growth factor binding protein 7 -3.70132
ANKRD10 ankyrin repeat domain 10 -3.01925
ARHGAP1 Rho GTPase activating protein 1 -2.20862
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.1928
TCEAL4 transcription elongation factor A (SII)-like 4 -2.06741