CRCGN015_MCF10A_48H:I24 Gene Set
Genes
48 genes differentially expressed following the CRCGN015_MCF10A_48H:I24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
BZW2
|
basic leucine zipper and W2 domains 2
|
5.0795
|
|
SNX11
|
sorting nexin 11
|
3.48248
|
|
WIF1
|
WNT inhibitory factor 1
|
3.1391
|
|
APOE
|
apolipoprotein E
|
2.79715
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
2.71065
|
|
PTBP2
|
polypyrimidine tract binding protein 2
|
2.379
|
|
THUMPD2
|
THUMP domain containing 2
|
2.3663
|
|
ATP6V1H
|
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
|
2.2908
|
|
GTF2F2
|
general transcription factor IIF, polypeptide 2, 30kDa
|
2.2797
|
|
CYP1A1
|
cytochrome P450, family 1, subfamily A, polypeptide 1
|
2.2588
|
|
MAP4K3
|
mitogen-activated protein kinase kinase kinase kinase 3
|
2.2504
|
|
FBRS
|
fibrosin
|
2.2233
|
|
UCHL3
|
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
|
2.216
|
|
MOK
|
MOK protein kinase
|
2.192
|
|
CBR4
|
carbonyl reductase 4
|
2.17945
|
|
ASB8
|
ankyrin repeat and SOCS box containing 8
|
2.1476
|
|
METTL22
|
methyltransferase like 22
|
2.12705
|
|
AOPEP
|
aminopeptidase O (putative)
|
2.1193
|
|
JUN
|
jun proto-oncogene
|
2.09375
|
|
ENTREP1
|
endosomal transmembrane epsin interactor 1
|
2.0722
|
|
NFATC3
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
|
2.0712
|
|
NAA60
|
N(alpha)-acetyltransferase 60, NatF catalytic subunit
|
2.06985
|
|
ZNF750
|
zinc finger protein 750
|
2.05395
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.05215
|
|
ZNF512B
|
zinc finger protein 512B
|
2.03962
|
|
ZKSCAN2
|
zinc finger with KRAB and SCAN domains 2
|
2.0285
|
|
TAOK3
|
TAO kinase 3
|
2.00135
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
S100A8
|
S100 calcium binding protein A8
|
-5.0
|
|
CYCS
|
cytochrome c, somatic
|
-4.9513
|
|
HEATR1
|
HEAT repeat containing 1
|
-4.10962
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-3.7634
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.47347
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-3.07947
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
-2.84065
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.6414
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
-2.5576
|
|
SLC35D2
|
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
|
-2.28907
|
|
SLC35B1
|
solute carrier family 35, member B1
|
-2.2758
|
|
NDUFS7
|
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
|
-2.26045
|
|
GRPEL1
|
GrpE-like 1, mitochondrial (E. coli)
|
-2.23738
|
|
TEX10
|
testis expressed 10
|
-2.234
|
|
HMG20B
|
high mobility group 20B
|
-2.16678
|
|
TBP
|
TATA box binding protein
|
-2.1479
|
|
ZBTB38
|
zinc finger and BTB domain containing 38
|
-2.1308
|
|
MRPS30
|
mitochondrial ribosomal protein S30
|
-2.12075
|
|
NDUFS5
|
NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)
|
-2.04505
|
|
COX5B
|
cytochrome c oxidase subunit Vb
|
-2.02547
|
|
TSPAN8
|
tetraspanin 8
|
-2.00295
|
