| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | hydrazobenzene 11.33 um perturbation at 48 h in MCF10A (Carcinogenome) |
| Similar Terms | |
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100 genes differentially expressed following the CRCGN015_MCF10A_48H:J03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRB10 | growth factor receptor-bound protein 10 | 5.02567 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 4.85239 |
| ANO10 | anoctamin 10 | 3.78476 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.31483 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | 3.30089 |
| VGLL4 | vestigial-like family member 4 | 3.21285 |
| RPN1 | ribophorin I | 2.99181 |
| CERK | ceramide kinase | 2.89454 |
| RIC8A | RIC8 guanine nucleotide exchange factor A | 2.8062 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 2.75373 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 2.72344 |
| SIRT3 | sirtuin 3 | 2.72276 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | 2.68082 |
| DDIT4 | DNA-damage-inducible transcript 4 | 2.46891 |
| EPCAM | epithelial cell adhesion molecule | 2.44381 |
| LYPLA2 | lysophospholipase II | 2.43168 |
| EVL | Enah/Vasp-like | 2.42471 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 2.3827 |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) | 2.35652 |
| AFG3L2 | AFG3-like AAA ATPase 2 | 2.33768 |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 2.28411 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 2.23853 |
| SDF2 | stromal cell-derived factor 2 | 2.23543 |
| TRAPPC4 | trafficking protein particle complex 4 | 2.2124 |
| GRAMD1B | GRAM domain containing 1B | 2.19043 |
| ARPC4-TTLL3 | ARPC4-TTLL3 readthrough | 2.18073 |
| AKR1A1 | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 2.1807 |
| CHURC1-FNTB | CHURC1-FNTB readthrough | 2.1786 |
| RNMT | RNA (guanine-7-) methyltransferase | 2.15133 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 2.14102 |
| GFUS | GDP-L-fucose synthase | 2.13774 |
| GRK2 | G protein-coupled receptor kinase 2 | 2.12748 |
| C2CD5 | C2 calcium-dependent domain containing 5 | 2.11183 |
| HDAC5 | histone deacetylase 5 | 2.10459 |
| CIRBP | cold inducible RNA binding protein | 2.10372 |
| HS1BP3 | HCLS1 binding protein 3 | 2.10144 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 2.09631 |
| STK25 | serine/threonine kinase 25 | 2.08843 |
| NELFB | negative elongation factor complex member B | 2.08537 |
| PLSCR3 | phospholipid scramblase 3 | 2.08082 |
| DPM2 | dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit | 2.07837 |
| TUBB4B | tubulin, beta 4B class IVb | 2.04253 |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 | 2.0405 |
| IER3 | immediate early response 3 | 2.03391 |
| MAPK3 | mitogen-activated protein kinase 3 | 2.03368 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | 2.00874 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 | 2.00648 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 2.00256 |
| REPS1 | RALBP1 associated Eps domain containing 1 | 2.00246 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SCYL3 | SCY1-like 3 (S. cerevisiae) | -4.93133 |
| KRT14 | keratin 14, type I | -4.63616 |
| SLC25A46 | solute carrier family 25, member 46 | -4.59546 |
| S100A8 | S100 calcium binding protein A8 | -4.58518 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -3.35512 |
| MICB | MHC class I polypeptide-related sequence B | -3.27266 |
| HEATR1 | HEAT repeat containing 1 | -3.13766 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | -2.75023 |
| ZNF764 | zinc finger protein 764 | -2.49064 |
| ZNF518A | zinc finger protein 518A | -2.48482 |
| LAMP3 | lysosomal-associated membrane protein 3 | -2.43382 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.39501 |
| DCAF17 | DDB1 and CUL4 associated factor 17 | -2.39241 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -2.35689 |
| LINS1 | lines homolog 1 | -2.35249 |
| ZNHIT6 | zinc finger, HIT-type containing 6 | -2.33285 |
| ZCCHC10 | zinc finger, CCHC domain containing 10 | -2.30223 |
| THAP10 | THAP domain containing 10 | -2.28757 |
| ZNF322 | zinc finger protein 322 | -2.28753 |
| CILK1 | ciliogenesis associated kinase 1 | -2.27892 |
| RBL1 | retinoblastoma-like 1 | -2.25795 |
| TSTD2 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 | -2.24652 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 | -2.24247 |
| ZNF217 | zinc finger protein 217 | -2.22771 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 | -2.2122 |
| DPP8 | dipeptidyl-peptidase 8 | -2.21009 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | -2.20925 |
| AKR1D1 | aldo-keto reductase family 1, member D1 | -2.19139 |
| TRIP12 | thyroid hormone receptor interactor 12 | -2.17676 |
| ARHGAP5 | Rho GTPase activating protein 5 | -2.15955 |
| AVIL | advillin | -2.13806 |
| HOXD1 | homeobox D1 | -2.13739 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) | -2.11361 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -2.0605 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | -2.05923 |
| SLAMF8 | SLAM family member 8 | -2.05694 |
| FOXL2 | forkhead box L2 | -2.05627 |
| PEX13 | peroxisomal biogenesis factor 13 | -2.05373 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | -2.0376 |
| CYP7A1 | cytochrome P450, family 7, subfamily A, polypeptide 1 | -2.03652 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.03328 |
| DOP1A | DOP1 leucine zipper like protein A | -2.02999 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -2.02997 |
| KIF11 | kinesin family member 11 | -2.02388 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 | -2.02251 |
| TRIM36 | tripartite motif containing 36 | -2.01789 |
| DMXL1 | Dmx-like 1 | -2.01783 |
| ATG12 | autophagy related 12 | -2.01288 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein | -2.01266 |
| CASD1 | CAS1 domain containing 1 | -2.00623 |
| DCP2 | decapping mRNA 2 | -2.00159 |
