CRCGN015_MCF10A_48H:J04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vinyl toluene 99.96 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN015_MCF10A_48H:J04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 4.82542
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 4.00128
BTK Bruton agammaglobulinemia tyrosine kinase 2.82253
MSRA methionine sulfoxide reductase A 2.14485
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 2.11616
SNTA1 syntrophin, alpha 1 2.10704
HOXC10 homeobox C10 2.0965
IPO13 importin 13 2.09248
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 2.09045
DCAF10 DDB1 and CUL4 associated factor 10 2.06649
FABP3 fatty acid binding protein 3, muscle and heart 2.04822
PKD2L1 polycystic kidney disease 2-like 1 2.03073

decreased expression

Symbol Name Standardized Value
CCNB1 cyclin B1 -4.73691
MT2A metallothionein 2A -4.56081
EIF5 eukaryotic translation initiation factor 5 -3.68001
GRN granulin -2.57386
ARL14 ADP-ribosylation factor-like 14 -2.53318
GLOD4 glyoxalase domain containing 4 -2.38623
PLK2 polo-like kinase 2 -2.28784
ZBTB35 zinc finger and BTB domain containing 35 -2.28305
CIB1 calcium and integrin binding 1 (calmyrin) -2.07302