CRCGN015_MCF10A_48H:J05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vinyl toluene 33.32 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

62 genes differentially expressed following the CRCGN015_MCF10A_48H:J05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.5557
GRB10 growth factor receptor-bound protein 10 3.42947
SSBP2 single-stranded DNA binding protein 2 3.41267
SMIM40 small integral membrane protein 40 3.32321
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.92161
ADAM10 ADAM metallopeptidase domain 10 2.8795
PRKCQ protein kinase C, theta 2.79943
LIG4 ligase IV, DNA, ATP-dependent 2.55923
OGDHL oxoglutarate dehydrogenase-like 2.45782
GABPA GA binding protein transcription factor, alpha subunit 60kDa 2.22833
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 2.22694
STX17 syntaxin 17 2.20137
PCM1 pericentriolar material 1 2.17719
ZMYM6 zinc finger, MYM-type 6 2.15582
RCOR3 REST corepressor 3 2.11494
B4GAT1 beta-1,4-glucuronyltransferase 1 2.10162
TWSG1 twisted gastrulation BMP signaling modulator 1 2.08289
MFSD6 major facilitator superfamily domain containing 6 2.08286
WDR33 WD repeat domain 33 2.08214
MAGEA12 melanoma antigen family A12 2.01314
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.00376
MAGEA1 melanoma antigen family A1 2.00297

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -3.26814
MSMO1 methylsterol monooxygenase 1 -3.25368
DYNLT3 dynein, light chain, Tctex-type 3 -3.24461
MRPS16 mitochondrial ribosomal protein S16 -3.1001
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -3.0379
KRT7 keratin 7, type II -2.8411
HEATR1 HEAT repeat containing 1 -2.69789
SLC35F2 solute carrier family 35, member F2 -2.68359
CRK v-crk avian sarcoma virus CT10 oncogene homolog -2.67589
FLCN folliculin -2.66733
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) -2.58773
YME1L1 YME1-like 1 ATPase -2.5512
SH2B2 SH2B adaptor protein 2 -2.47754
ZDHHC6 zinc finger, DHHC-type containing 6 -2.4343
TM9SF3 transmembrane 9 superfamily member 3 -2.41538
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -2.36344
TERF2 telomeric repeat binding factor 2 -2.27259
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled -2.20673
PTGDS prostaglandin D2 synthase 21kDa (brain) -2.20625
RND3 Rho family GTPase 3 -2.2008
FOXJ3 forkhead box J3 -2.19482
PPP2R2D protein phosphatase 2, regulatory subunit B, delta -2.16559
ZNF611 zinc finger protein 611 -2.1488
JOSD1 Josephin domain containing 1 -2.13028
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.12407
RLBP1 retinaldehyde binding protein 1 -2.1152
DCLRE1B DNA cross-link repair 1B -2.10693
GMEB1 glucocorticoid modulatory element binding protein 1 -2.09616
PPDPF pancreatic progenitor cell differentiation and proliferation factor -2.0882
GLRX2 glutaredoxin 2 -2.06122
NME6 NME/NM23 nucleoside diphosphate kinase 6 -2.04925
DCAF10 DDB1 and CUL4 associated factor 10 -2.03388
RGSL1 regulator of G-protein signaling like 1 -2.03042
RGS18 regulator of G-protein signaling 18 -2.03014
GMPPB GDP-mannose pyrophosphorylase B -2.03008
GPAA1 glycosylphosphatidylinositol anchor attachment 1 -2.02829
HPS6 Hermansky-Pudlak syndrome 6 -2.01833
CNTNAP1 contactin associated protein 1 -2.01776
GFRA2 GDNF family receptor alpha 2 -2.01506
NHLRC2 NHL repeat containing 2 -2.00134