CRCGN015_MCF10A_48H:J09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ethinyl estradiol 11.03 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN015_MCF10A_48H:J09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 6.36804
PNKP polynucleotide kinase 3'-phosphatase 5.33721
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.98171
DHDDS dehydrodolichyl diphosphate synthase 2.90708
MAP3K4 mitogen-activated protein kinase kinase kinase 4 2.63043
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 2.50826
CLSTN2 calsyntenin 2 2.45625
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 2.2439
TBX19 T-box 19 2.23362
WFS1 Wolfram syndrome 1 (wolframin) 2.17551
THBS4 thrombospondin 4 2.15207
AGO2 argonaute RISC catalytic component 2 2.15136
EPB41L5 erythrocyte membrane protein band 4.1 like 5 2.06062
RNMT RNA (guanine-7-) methyltransferase 2.055
TRIM9 tripartite motif containing 9 2.01121

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -4.26629
KRT14 keratin 14, type I -4.15185
MT2A metallothionein 2A -3.53419
LOC124907782 dual specificity protein phosphatase 22 -3.14245
TSPAN4 tetraspanin 4 -2.73842
HMG20B high mobility group 20B -2.62154
CRCT1 cysteine-rich C-terminal 1 -2.34397
CLDND1 claudin domain containing 1 -2.11896
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -2.10887
HEBP1 heme binding protein 1 -2.04714