CRCGN015_MCF10A_48H:J14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-nitrosodiethylamine 33.43 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

13 genes differentially expressed following the CRCGN015_MCF10A_48H:J14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CETN3 centrin, EF-hand protein, 3 3.32009
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.27545
PRKCQ protein kinase C, theta 3.18839
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.63802
PFKL phosphofructokinase, liver 2.36783
SNX11 sorting nexin 11 2.2972

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -4.57766
MT2A metallothionein 2A -3.85384
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) -3.40477
RPA3 replication protein A3, 14kDa -3.30812
RNF167 ring finger protein 167 -3.26795
TSPAN4 tetraspanin 4 -3.08408
C4A complement component 4A (Rodgers blood group) -2.0687