CRCGN015_MCF10A_48H:J20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description simazine 34.02 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN015_MCF10A_48H:J20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 4.9837
ZW10 zw10 kinetochore protein 3.5105
CCDC92 coiled-coil domain containing 92 3.37578
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.05493
DHDDS dehydrodolichyl diphosphate synthase 2.57545
MTA2 metastasis associated 1 family, member 2 2.4455
NT5DC2 5'-nucleotidase domain containing 2 2.43398
THSD1 thrombospondin, type I, domain containing 1 2.32417
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 2.20262
LEP leptin 2.02319

decreased expression

Symbol Name Standardized Value
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.35702
MTO1 mitochondrial tRNA translation optimization 1 -2.64427
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.58639
CANT1 calcium activated nucleotidase 1 -2.45263
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 -2.22506
CDPF1 cysteine-rich, DPF motif domain containing 1 -2.14553