CRCGN015_MCF10A_48H:J21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description simazine 11.34 um perturbation at 48 h in MCF10A (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

20 genes differentially expressed following the CRCGN015_MCF10A_48H:J21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MCOLN1 mucolipin 1 4.91389
STAP2 signal transducing adaptor family member 2 3.44869
GRWD1 glutamate-rich WD repeat containing 1 3.08942
GSTZ1 glutathione S-transferase zeta 1 2.98236
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 2.68623
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 2.63296
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 2.57954
MRC1 mannose receptor, C type 1 2.37724
PCM1 pericentriolar material 1 2.1808
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.00581

decreased expression

Symbol Name Standardized Value
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -4.35959
BIRC2 baculoviral IAP repeat containing 2 -3.72574
ANXA3 annexin A3 -2.89533
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.88138
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) -2.61292
PRSS23 protease, serine, 23 -2.45342
TRAPPC3 trafficking protein particle complex 3 -2.43614
CXCR2 chemokine (C-X-C motif) receptor 2 -2.15988
CX3CR1 chemokine (C-X3-C motif) receptor 1 -2.02149
TMEM123 transmembrane protein 123 -2.01821