CRCGN015_MCF10A_48H:K02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,4-dichlorophenol 33.1 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN015_MCF10A_48H:K02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FPGS folylpolyglutamate synthase 3.98678
IGHMBP2 immunoglobulin mu binding protein 2 2.84565
MRPS22 mitochondrial ribosomal protein S22 2.6505
ATRAID all-trans retinoic acid-induced differentiation factor 2.41649
KLHL21 kelch-like family member 21 2.19374
ZNHIT3 zinc finger, HIT-type containing 3 2.16607
REPS2 RALBP1 associated Eps domain containing 2 2.12927
CLCNKB chloride channel, voltage-sensitive Kb 2.11611
RAB30 RAB30, member RAS oncogene family 2.10542
IGLL1 immunoglobulin lambda-like polypeptide 1 2.1018
DERL2 derlin 2 2.08533
OARD1 O-acyl-ADP-ribose deacylase 1 2.0742
CLCNKA chloride channel, voltage-sensitive Ka 2.06769
TXNL4B thioredoxin-like 4B 2.06414
MAP3K4 mitogen-activated protein kinase kinase kinase 4 2.04982

decreased expression

Symbol Name Standardized Value
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -3.50187
MLEC malectin -3.44385
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -3.26301
CANT1 calcium activated nucleotidase 1 -3.0265
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -2.91418
VAT1 vesicle amine transport 1 -2.73639
DUSP6 dual specificity phosphatase 6 -2.59743
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -2.48261
HMG20B high mobility group 20B -2.31453
ZNF106 zinc finger protein 106 -2.18538
TAOK3 TAO kinase 3 -2.15988
STARD3 StAR-related lipid transfer (START) domain containing 3 -2.14141
MTMR11 myotubularin related protein 11 -2.11705
LINC02762 long intergenic non-protein coding RNA 2762 -2.09317