CRCGN015_MCF10A_48H:K03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,4-dichlorophenol 11.03 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

13 genes differentially expressed following the CRCGN015_MCF10A_48H:K03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 4.68848
SLC26A2 solute carrier family 26 (anion exchanger), member 2 2.51069
SIRT3 sirtuin 3 2.27086
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.10718
OCEL1 occludin/ELL domain containing 1 2.10554
IRAK4 interleukin-1 receptor-associated kinase 4 2.07594
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 2.06868

decreased expression

Symbol Name Standardized Value
ARPP19 cAMP-regulated phosphoprotein, 19kDa -3.9802
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.21618
GGCT gamma-glutamylcyclotransferase -2.5073
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -2.34796
MT2A metallothionein 2A -2.07496
IGFBP7 insulin-like growth factor binding protein 7 -2.04384