CRCGN015_MCF10A_48H:K04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dimethoxane 98.8 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

48 genes differentially expressed following the CRCGN015_MCF10A_48H:K04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ZNF586 zinc finger protein 586 4.20982
PRKCH protein kinase C, eta 4.08149
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.90815
ZNF544 zinc finger protein 544 3.58619
ZNF419 zinc finger protein 419 3.23728
ZNF551 zinc finger protein 551 2.65186
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 2.64073
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 2.50765
YAP1 Yes-associated protein 1 2.47332
PLA2G3 phospholipase A2, group III 2.43792
TUBA3E tubulin, alpha 3e 2.38436
PCDHGA3 protocadherin gamma subfamily A, 3 2.36574
CSAG2 CSAG family, member 2 2.34185
ZNF134 zinc finger protein 134 2.31666
ZNF550 zinc finger protein 550 2.28342
AURKC aurora kinase C 2.25785
RPAP2 RNA polymerase II associated protein 2 2.24394
HSPA1L heat shock 70kDa protein 1-like 2.24252
CCR3 chemokine (C-C motif) receptor 3 2.22459
MGAM maltase-glucoamylase 2.21477
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1 2.1629
ZNF426 zinc finger protein 426 2.15639
EXOSC5 exosome component 5 2.14925
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa 2.08083
AARS1 alanyl-tRNA synthetase 1 2.05668
APOC3 apolipoprotein C-III 2.04487
ZKSCAN4 zinc finger with KRAB and SCAN domains 4 2.0214
EXOSC4 exosome component 4 2.00775
PECR peroxisomal trans-2-enoyl-CoA reductase 2.00423
TUBA3C tubulin, alpha 3c 2.00296
KLF3 Kruppel-like factor 3 (basic) 2.002

decreased expression

Symbol Name Standardized Value
NPDC1 neural proliferation, differentiation and control, 1 -5.07422
COG2 component of oligomeric golgi complex 2 -4.55479
LDHD lactate dehydrogenase D -4.39972
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.25734
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -3.55552
COG5 component of oligomeric golgi complex 5 -2.86036
KRT14 keratin 14, type I -2.61278
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -2.55925
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 -2.32891
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -2.25408
LAMB1 laminin, beta 1 -2.25405
HEBP1 heme binding protein 1 -2.14839
RINT1 RAD50 interactor 1 -2.13287
ARAF A-Raf proto-oncogene, serine/threonine kinase -2.107
TM9SF3 transmembrane 9 superfamily member 3 -2.08614
DENR density-regulated protein -2.02507
CYBA cytochrome b-245, alpha polypeptide -2.01736