CRCGN015_MCF10A_48H:K06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dimethoxane 10.98 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN015_MCF10A_48H:K06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HBA1 hemoglobin, alpha 1 4.53601
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 3.6459
MCOLN1 mucolipin 1 3.18894
WIF1 WNT inhibitory factor 1 3.01574
KDM5D lysine (K)-specific demethylase 5D 2.7174
CXCR4 chemokine (C-X-C motif) receptor 4 2.48574
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.47274
CD5L CD5 molecule-like 2.35887
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.30148
BCL7A B-cell CLL/lymphoma 7A 2.21953
PNPLA6 patatin-like phospholipase domain containing 6 2.06996
TRAP1 TNF receptor-associated protein 1 2.03392
LZTFL1 leucine zipper transcription factor-like 1 2.01572
TAC4 tachykinin 4 (hemokinin) 2.00485

decreased expression

Symbol Name Standardized Value
CRK v-crk avian sarcoma virus CT10 oncogene homolog -3.88093
ADI1 acireductone dioxygenase 1 -3.83432
BAG3 BCL2-associated athanogene 3 -3.46861
NCK1 NCK adaptor protein 1 -3.38207
FOXJ3 forkhead box J3 -2.76085
FASTKD5 FAST kinase domains 5 -2.54738
AKIRIN1 akirin 1 -2.37042
PIAS3 protein inhibitor of activated STAT, 3 -2.30965
TCIM transcriptional and immune response regulator -2.13642
ITGAV integrin, alpha V -2.10786
CALCB calcitonin-related polypeptide beta -2.01973
USP9X ubiquitin specific peptidase 9, X-linked -2.00822