CRCGN015_MCF10A_48H:K12 Gene Set
Genes
44 genes differentially expressed following the CRCGN015_MCF10A_48H:K12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CNPY3
|
canopy FGF signaling regulator 3
|
4.81548
|
|
RIC8A
|
RIC8 guanine nucleotide exchange factor A
|
2.68082
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
2.62544
|
|
SMPD4
|
sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
|
2.54093
|
|
SIRT3
|
sirtuin 3
|
2.34679
|
|
PGGHG
|
protein-glucosylgalactosylhydroxylysine glucosidase
|
2.32641
|
|
CLN6
|
ceroid-lipofuscinosis, neuronal 6, late infantile, variant
|
2.30194
|
|
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta
|
2.26795
|
|
FZD1
|
frizzled class receptor 1
|
2.22304
|
|
COL4A1
|
collagen, type IV, alpha 1
|
2.22191
|
|
NCAPH
|
non-SMC condensin I complex, subunit H
|
2.21578
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
2.1994
|
|
MUTYH
|
mutY homolog
|
2.14393
|
|
QTRT2
|
queuine tRNA-ribosyltransferase accessory subunit 2
|
2.13412
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.10572
|
|
FAM193A
|
family with sequence similarity 193, member A
|
2.08742
|
|
NAP1L4
|
nucleosome assembly protein 1-like 4
|
2.06894
|
|
ABCC10
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
|
2.02263
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MSMO1
|
methylsterol monooxygenase 1
|
-5.45957
|
|
DECR1
|
2,4-dienoyl CoA reductase 1, mitochondrial
|
-4.01906
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
-3.10271
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
-2.85859
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.56439
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.55188
|
|
PEX2
|
peroxisomal biogenesis factor 2
|
-2.55122
|
|
RPS5
|
ribosomal protein S5
|
-2.47664
|
|
PCBD1
|
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
|
-2.46633
|
|
GDE1
|
glycerophosphodiester phosphodiesterase 1
|
-2.46479
|
|
UBE2W
|
ubiquitin-conjugating enzyme E2W (putative)
|
-2.45097
|
|
PPIP5K1
|
diphosphoinositol pentakisphosphate kinase 1
|
-2.37476
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
-2.29003
|
|
LYRM1
|
LYR motif containing 1
|
-2.28968
|
|
BNIP3L
|
BCL2/adenovirus E1B 19kDa interacting protein 3-like
|
-2.24932
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
-2.22266
|
|
ZNF226
|
zinc finger protein 226
|
-2.20842
|
|
MBD5
|
methyl-CpG binding domain protein 5
|
-2.19722
|
|
GLRX
|
glutaredoxin (thioltransferase)
|
-2.19702
|
|
ELP4
|
elongator acetyltransferase complex subunit 4
|
-2.14937
|
|
AKR1C3
|
aldo-keto reductase family 1, member C3
|
-2.14318
|
|
S100A8
|
S100 calcium binding protein A8
|
-2.13114
|
|
FAH
|
fumarylacetoacetate hydrolase (fumarylacetoacetase)
|
-2.12863
|
|
SNX2
|
sorting nexin 2
|
-2.08823
|
|
STXBP2
|
syntaxin binding protein 2
|
-2.0484
|
|
SCAND1
|
SCAN domain containing 1
|
-2.04799
|
