CRCGN015_MCF10A_48H:K14 Gene Set
Genes
49 genes differentially expressed following the CRCGN015_MCF10A_48H:K14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
4.90272
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.86577
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
4.57577
|
|
GATA3
|
GATA binding protein 3
|
4.27788
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
3.44747
|
|
WASF3
|
WAS protein family, member 3
|
3.30323
|
|
IKBKB
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
|
2.70861
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
2.63572
|
|
STIMATE
|
STIM activating enhancer
|
2.36186
|
|
ABHD11
|
abhydrolase domain containing 11
|
2.31719
|
|
SS18
|
synovial sarcoma translocation, chromosome 18
|
2.12229
|
|
STEAP4
|
STEAP family member 4
|
2.09309
|
|
NSMCE4A
|
non-SMC element 4 homolog A (S. cerevisiae)
|
2.0805
|
|
NDUFAF3
|
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
|
2.06213
|
|
RPE
|
ribulose-5-phosphate-3-epimerase
|
2.03965
|
|
SLC29A2
|
solute carrier family 29 (equilibrative nucleoside transporter), member 2
|
2.03149
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
2.02965
|
|
MAP3K5
|
mitogen-activated protein kinase kinase kinase 5
|
2.01905
|
|
MFSD6
|
major facilitator superfamily domain containing 6
|
2.01679
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PGAM4
|
phosphoglycerate mutase family member 4
|
-4.78204
|
|
S100A8
|
S100 calcium binding protein A8
|
-4.51023
|
|
KRT14
|
keratin 14, type I
|
-4.08914
|
|
PLK2
|
polo-like kinase 2
|
-3.34389
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.76378
|
|
UFM1
|
ubiquitin-fold modifier 1
|
-2.54431
|
|
TPI1
|
triosephosphate isomerase 1
|
-2.50697
|
|
P4HA1
|
prolyl 4-hydroxylase, alpha polypeptide I
|
-2.41707
|
|
TRIM21
|
tripartite motif containing 21
|
-2.37355
|
|
USB1
|
U6 snRNA biogenesis 1
|
-2.36086
|
|
COX6A1
|
cytochrome c oxidase subunit VIa polypeptide 1
|
-2.31591
|
|
RPN2
|
ribophorin II
|
-2.20855
|
|
EHHADH
|
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
|
-2.19493
|
|
ALG11
|
ALG11, alpha-1,2-mannosyltransferase
|
-2.17175
|
|
GCHFR
|
GTP cyclohydrolase I feedback regulator
|
-2.15621
|
|
CCL3L3
|
chemokine (C-C motif) ligand 3-like 3
|
-2.14452
|
|
COL11A2
|
collagen, type XI, alpha 2
|
-2.14049
|
|
PGK1
|
phosphoglycerate kinase 1
|
-2.13433
|
|
COL9A1
|
collagen, type IX, alpha 1
|
-2.12358
|
|
CLDN6
|
claudin 6
|
-2.09948
|
|
PIGZ
|
phosphatidylinositol glycan anchor biosynthesis, class Z
|
-2.08712
|
|
ADPGK
|
ADP-dependent glucokinase
|
-2.07465
|
|
NPTN
|
neuroplastin
|
-2.07363
|
|
MMP13
|
matrix metallopeptidase 13
|
-2.06115
|
|
CCL4
|
chemokine (C-C motif) ligand 4
|
-2.06033
|
|
VKORC1
|
vitamin K epoxide reductase complex, subunit 1
|
-2.03939
|
|
WNT10B
|
wingless-type MMTV integration site family, member 10B
|
-2.02723
|
|
MAD2L1BP
|
MAD2L1 binding protein
|
-2.02378
|
|
PKM
|
pyruvate kinase, muscle
|
-2.01394
|
|
ABTB2
|
ankyrin repeat and BTB (POZ) domain containing 2
|
-2.00275
|
