CRCGN015_MCF10A_48H:K16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isobutyraldehyde 101.79 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN015_MCF10A_48H:K16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.48268
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 3.46939
TIAM1 T-cell lymphoma invasion and metastasis 1 3.30691
PRR7 proline rich 7 (synaptic) 3.14889
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 3.07436
FRS2 fibroblast growth factor receptor substrate 2 3.01538
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.94491
GSTZ1 glutathione S-transferase zeta 1 2.94306
NT5DC2 5'-nucleotidase domain containing 2 2.91059
CHMP6 charged multivesicular body protein 6 2.80147
KIFBP kinesin family binding protein 2.79993
CETN3 centrin, EF-hand protein, 3 2.64099
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.18404

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -4.12832
CCNB1 cyclin B1 -3.46803
BAG3 BCL2-associated athanogene 3 -2.86574
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.19892
RGS16 regulator of G-protein signaling 16 -2.07107
ATP11B ATPase, class VI, type 11B -2.07044