CRCGN015_MCF10A_48H:K18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isobutyraldehyde 11.31 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

43 genes differentially expressed following the CRCGN015_MCF10A_48H:K18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
WIF1 WNT inhibitory factor 1 4.39596
LAGE3 L antigen family, member 3 4.38945
STK10 serine/threonine kinase 10 4.32779
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.32114
GPATCH8 G patch domain containing 8 2.71096
NUCB2 nucleobindin 2 2.41981
PDPN podoplanin 2.34165
CHEK2 checkpoint kinase 2 2.33627
THRAP3 thyroid hormone receptor associated protein 3 2.3167
EPPK1 epiplakin 1 2.27952
HBA1 hemoglobin, alpha 1 2.25892
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 2.25522
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 2.19458
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 2.16069
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.14963
TBCCD1 TBCC domain containing 1 2.14797
STRN3 striatin, calmodulin binding protein 3 2.14718
PRPF39 pre-mRNA processing factor 39 2.13886
IFITM2 interferon induced transmembrane protein 2 2.13594
MTA2 metastasis associated 1 family, member 2 2.12387
SRSF6 serine/arginine-rich splicing factor 6 2.09669
CDC23 cell division cycle 23 2.07921
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 2.06065
FAF2 Fas associated factor family member 2 2.06054
SFMBT1 Scm-like with four mbt domains 1 2.02214
PDE3B phosphodiesterase 3B, cGMP-inhibited 2.01818
IFITM3 interferon induced transmembrane protein 3 2.00602

decreased expression

Symbol Name Standardized Value
TXNDC9 thioredoxin domain containing 9 -4.07199
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.94748
PDCD10 programmed cell death 10 -2.54162
LMAN2L lectin, mannose-binding 2-like -2.32128
CRYM crystallin, mu -2.23502
ZMIZ1 zinc finger, MIZ-type containing 1 -2.17768
RPS5 ribosomal protein S5 -2.15871
ATG3 autophagy related 3 -2.15074
PDCL3 phosducin-like 3 -2.11437
UNC50 unc-50 homolog (C. elegans) -2.11081
ZSCAN16 zinc finger and SCAN domain containing 16 -2.11034
MBNL2 muscleblind-like splicing regulator 2 -2.06693
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -2.04575
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -2.01435
THAP1 THAP domain containing, apoptosis associated protein 1 -2.01381
SDF2 stromal cell-derived factor 2 -2.00376