CRCGN015_MCF10A_48H:K21 Gene Set
Genes
36 genes differentially expressed following the CRCGN015_MCF10A_48H:K21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STK10
|
serine/threonine kinase 10
|
4.85451
|
|
HYOU1
|
hypoxia up-regulated 1
|
3.60843
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
3.29045
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
3.13713
|
|
TLK2
|
tousled-like kinase 2
|
3.04724
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.93592
|
|
UPP1
|
uridine phosphorylase 1
|
2.30865
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
2.3004
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.21078
|
|
TIMP2
|
TIMP metallopeptidase inhibitor 2
|
2.14733
|
|
TRAPPC6A
|
trafficking protein particle complex 6A
|
2.12552
|
|
RUFY1
|
RUN and FYVE domain containing 1
|
2.07692
|
|
ARL2BP
|
ADP-ribosylation factor-like 2 binding protein
|
2.06607
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
2.06019
|
|
ZNF354A
|
zinc finger protein 354A
|
2.05118
|
|
GUSB
|
glucuronidase, beta
|
2.01341
|
|
ANGPT2
|
angiopoietin 2
|
2.01088
|
|
DNMT3L
|
DNA (cytosine-5-)-methyltransferase 3-like
|
2.00659
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PSMD10
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
|
-5.18028
|
|
CD44
|
CD44 molecule (Indian blood group)
|
-3.53508
|
|
ZBTB35
|
zinc finger and BTB domain containing 35
|
-2.88157
|
|
PLK2
|
polo-like kinase 2
|
-2.60144
|
|
ISOC1
|
isochorismatase domain containing 1
|
-2.5977
|
|
BBOF1
|
basal body orientation factor 1
|
-2.44641
|
|
ATG4A
|
autophagy related 4A, cysteine peptidase
|
-2.2585
|
|
SYT2
|
synaptotagmin II
|
-2.24587
|
|
MT2A
|
metallothionein 2A
|
-2.22275
|
|
HS1BP3
|
HCLS1 binding protein 3
|
-2.21215
|
|
PADI1
|
peptidyl arginine deiminase, type I
|
-2.18747
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.1848
|
|
TPPP3
|
tubulin polymerization-promoting protein family member 3
|
-2.1795
|
|
KCNS1
|
potassium voltage-gated channel, modifier subfamily S, member 1
|
-2.15758
|
|
TBP
|
TATA box binding protein
|
-2.10162
|
|
AZIN2
|
antizyme inhibitor 2
|
-2.05458
|
|
BRD3
|
bromodomain containing 3
|
-2.04037
|
|
SETD5
|
SET domain containing 5
|
-2.00987
|
