CRCGN015_MCF10A_48H:K23 Gene Set
Genes
40 genes differentially expressed following the CRCGN015_MCF10A_48H:K23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SPAG4
|
sperm associated antigen 4
|
5.0815
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.96977
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
4.8732
|
|
BUB1B
|
BUB1 mitotic checkpoint serine/threonine kinase B
|
3.171
|
|
FSD1
|
fibronectin type III and SPRY domain containing 1
|
2.9175
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
2.7543
|
|
PPM1G
|
protein phosphatase, Mg2+/Mn2+ dependent, 1G
|
2.5929
|
|
KDM5D
|
lysine (K)-specific demethylase 5D
|
2.5438
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
2.48158
|
|
IGFBP6
|
insulin-like growth factor binding protein 6
|
2.4343
|
|
PDIA2
|
protein disulfide isomerase family A, member 2
|
2.4247
|
|
BMP4
|
bone morphogenetic protein 4
|
2.34125
|
|
WDR37
|
WD repeat domain 37
|
2.29505
|
|
EIF1AY
|
eukaryotic translation initiation factor 1A, Y-linked
|
2.27113
|
|
MTREX
|
Mtr4 exosome RNA helicase
|
2.2518
|
|
JAKMIP2
|
janus kinase and microtubule interacting protein 2
|
2.24833
|
|
CHEK2
|
checkpoint kinase 2
|
2.1946
|
|
S100A3
|
S100 calcium binding protein A3
|
2.1688
|
|
PGC
|
progastricsin (pepsinogen C)
|
2.0444
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
2.0436
|
|
PCNT
|
pericentrin
|
2.03285
|
|
FANCC
|
Fanconi anemia, complementation group C
|
2.01755
|
|
TMEM51
|
transmembrane protein 51
|
2.0042
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-5.0
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.5203
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
-4.24045
|
|
SMC1A
|
structural maintenance of chromosomes 1A
|
-3.21668
|
|
MT2A
|
metallothionein 2A
|
-3.04935
|
|
NINJ2
|
ninjurin 2
|
-2.8128
|
|
LDHB
|
lactate dehydrogenase B
|
-2.6693
|
|
SKIC8
|
SKI8 subunit of superkiller complex
|
-2.59893
|
|
PUDP
|
pseudouridine 5'-phosphatase
|
-2.44325
|
|
PDLIM1
|
PDZ and LIM domain 1
|
-2.44315
|
|
EIF2B2
|
eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
|
-2.2887
|
|
LSM2
|
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.27485
|
|
CD24
|
CD24 molecule
|
-2.23027
|
|
COL21A1
|
collagen, type XXI, alpha 1
|
-2.08925
|
|
TP53BP2
|
tumor protein p53 binding protein 2
|
-2.0467
|
|
SF3B5
|
splicing factor 3b, subunit 5, 10kDa
|
-2.0327
|
|
NEDD9
|
neural precursor cell expressed, developmentally down-regulated 9
|
-2.03203
|
