CRCGN015_MCF10A_48H:K24 Gene Set
Genes
36 genes differentially expressed following the CRCGN015_MCF10A_48H:K24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PRKCH
|
protein kinase C, eta
|
4.75917
|
|
HBA1
|
hemoglobin, alpha 1
|
4.1505
|
|
SIRT3
|
sirtuin 3
|
3.69795
|
|
PYCR1
|
pyrroline-5-carboxylate reductase 1
|
2.9731
|
|
WASF3
|
WAS protein family, member 3
|
2.76935
|
|
RIC8A
|
RIC8 guanine nucleotide exchange factor A
|
2.7616
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
2.6778
|
|
GLI3
|
GLI family zinc finger 3
|
2.58425
|
|
TMEM80
|
transmembrane protein 80
|
2.32538
|
|
IFITM3
|
interferon induced transmembrane protein 3
|
2.27515
|
|
DEAF1
|
DEAF1 transcription factor
|
2.2417
|
|
HPN
|
hepsin
|
2.1363
|
|
PSMD13
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
|
2.0872
|
|
CPA4
|
carboxypeptidase A4
|
2.0538
|
|
CEP70
|
centrosomal protein 70kDa
|
2.04555
|
|
GATA2
|
GATA binding protein 2
|
2.00525
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.49265
|
|
LPGAT1
|
lysophosphatidylglycerol acyltransferase 1
|
-3.7882
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-3.7756
|
|
GRN
|
granulin
|
-3.41252
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
-2.6596
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.50455
|
|
GFUS
|
GDP-L-fucose synthase
|
-2.4968
|
|
ELOVL4
|
ELOVL fatty acid elongase 4
|
-2.34095
|
|
VIM
|
vimentin
|
-2.24505
|
|
CD48
|
CD48 molecule
|
-2.23195
|
|
NLRP2B
|
NLR family pyrin domain containing 2B
|
-2.2317
|
|
HEBP1
|
heme binding protein 1
|
-2.17115
|
|
SORBS3
|
sorbin and SH3 domain containing 3
|
-2.16985
|
|
CHMP2A
|
charged multivesicular body protein 2A
|
-2.1411
|
|
PRPF38B
|
pre-mRNA processing factor 38B
|
-2.12743
|
|
POF1B
|
premature ovarian failure, 1B
|
-2.1015
|
|
TMED3
|
transmembrane emp24 protein transport domain containing 3
|
-2.0747
|
|
MFHAS1
|
malignant fibrous histiocytoma amplified sequence 1
|
-2.0457
|
|
UBA2
|
ubiquitin-like modifier activating enzyme 2
|
-2.04345
|
|
SLC35A1
|
solute carrier family 35 (CMP-sialic acid transporter), member A1
|
-2.02375
|
