| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-phenyl-p-phenylenediamine.hcl 10.98 um perturbation at 48 h in MCF10A (Carcinogenome) |
| Similar Terms | |
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64 genes differentially expressed following the CRCGN015_MCF10A_48H:L06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HBA1 | hemoglobin, alpha 1 | 4.96488 |
| MAMLD1 | mastermind-like domain containing 1 | 4.31309 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.76561 |
| KLHL21 | kelch-like family member 21 | 3.48927 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 3.34667 |
| BMP4 | bone morphogenetic protein 4 | 3.02363 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | 2.47967 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.45372 |
| SYBU | syntabulin (syntaxin-interacting) | 2.28388 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 2.28373 |
| CORO1A | coronin, actin binding protein, 1A | 2.27419 |
| FOXI1 | forkhead box I1 | 2.2483 |
| E2F5 | E2F transcription factor 5, p130-binding | 2.23478 |
| CREB5 | cAMP responsive element binding protein 5 | 2.23095 |
| FMNL1 | formin-like 1 | 2.22345 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 2.21552 |
| KRT83 | keratin 83, type II | 2.16696 |
| CYP3A7-CYP3A51P | CYP3A7-CYP3A51P readthrough | 2.13497 |
| NDUFA10 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | 2.13022 |
| TMEM35A | transmembrane protein 35A | 2.11044 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 2.09613 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | 2.08801 |
| CYSLTR2 | cysteinyl leukotriene receptor 2 | 2.05223 |
| PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator | 2.04157 |
| THAP4 | THAP domain containing 4 | 2.04016 |
| PRDM13 | PR domain containing 13 | 2.0329 |
| CLEC5A | C-type lectin domain family 5, member A | 2.0315 |
| SLC6A7 | solute carrier family 6 (neurotransmitter transporter), member 7 | 2.03043 |
| KCNA1 | potassium channel, voltage gated shaker related subfamily A, member 1 | 2.02928 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.02244 |
| RUBCNL | rubicon like autophagy enhancer | 2.00823 |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 | 2.00733 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 2.00634 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -6.78389 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -4.40059 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -4.32461 |
| NUP85 | nucleoporin 85kDa | -3.9556 |
| ANXA3 | annexin A3 | -3.88415 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.52095 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -3.4927 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -3.42982 |
| SUMO4 | small ubiquitin-like modifier 4 | -3.04404 |
| MRPL58 | mitochondrial ribosomal protein L58 | -2.8763 |
| MRPS7 | mitochondrial ribosomal protein S7 | -2.73842 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -2.63188 |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) | -2.59461 |
| MORF4L2 | mortality factor 4 like 2 | -2.51356 |
| FOXJ3 | forkhead box J3 | -2.47857 |
| GRB2 | growth factor receptor-bound protein 2 | -2.47824 |
| LINC02762 | long intergenic non-protein coding RNA 2762 | -2.37689 |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl | -2.34575 |
| ATP5PD | ATP synthase peripheral stalk subunit d | -2.34335 |
| JPT1 | Jupiter microtubule associated homolog 1 | -2.32736 |
| HDAC1 | histone deacetylase 1 | -2.23009 |
| PCNA | proliferating cell nuclear antigen | -2.20355 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | -2.0665 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -2.056 |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) | -2.04765 |
| LDHB | lactate dehydrogenase B | -2.0443 |
| RPL38 | ribosomal protein L38 | -2.04398 |
| INTS13 | integrator complex subunit 13 | -2.04155 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.04012 |
| CSTF2 | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa | -2.03493 |
| WDR6 | WD repeat domain 6 | -2.03341 |
