CRCGN015_MCF10A_48H:L07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description iq 95.81 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

566 genes differentially expressed following the CRCGN015_MCF10A_48H:L07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PNKP polynucleotide kinase 3'-phosphatase 4.92181
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 4.69202
HSPB1 heat shock 27kDa protein 1 4.6844
CASC3 cancer susceptibility candidate 3 4.25111
DUSP14 dual specificity phosphatase 14 3.92564
AARS1 alanyl-tRNA synthetase 1 3.8519
RHEB Ras homolog enriched in brain 3.80412
TGFB3 transforming growth factor, beta 3 3.74717
CHMP2A charged multivesicular body protein 2A 3.63447
CCDC86 coiled-coil domain containing 86 3.62081
COG5 component of oligomeric golgi complex 5 3.59932
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 3.50204
CARS1 cysteinyl-tRNA synthetase 1 3.48214
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 3.47362
PYCR1 pyrroline-5-carboxylate reductase 1 3.47089
ANO10 anoctamin 10 3.44283
MKNK1 MAP kinase interacting serine/threonine kinase 1 3.40139
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 3.37691
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 3.37416
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 3.37259
PLA2G15 phospholipase A2, group XV 3.32166
LOC124908558 X antigen family member 1-like 3.31938
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 3.29804
DHRS7 dehydrogenase/reductase (SDR family) member 7 3.25542
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 3.24689
TMEM147 transmembrane protein 147 3.2114
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 3.20564
DROSHA drosha, ribonuclease type III 3.19777
METTL25B methyltransferase like 25B 3.19648
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 3.16131
INTS3 integrator complex subunit 3 3.14099
RAB27A RAB27A, member RAS oncogene family 3.12209
FASTK Fas-activated serine/threonine kinase 3.1103
MYO1D myosin ID 3.10825
RCE1 Ras converting CAAX endopeptidase 1 3.09431
MYO5A myosin VA (heavy chain 12, myoxin) 3.08568
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 3.08267
DHPS deoxyhypusine synthase 3.0798
DMAC2 distal membrane arm assembly component 2 3.06524
RBM42 RNA binding motif protein 42 3.06257
ZNF571 zinc finger protein 571 3.0624
TRAPPC3 trafficking protein particle complex 3 3.04508
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 3.02599
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 2.99439
ETHE1 ethylmalonic encephalopathy 1 2.99387
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing 2.9735
KRT16 keratin 16, type I 2.96788
TMEM50A transmembrane protein 50A 2.96048
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 2.95768
MECR mitochondrial trans-2-enoyl-CoA reductase 2.95072
KRT6A keratin 6A, type II 2.90689
MED24 mediator complex subunit 24 2.87502
ERCC2 excision repair cross-complementation group 2 2.83839
TYR tyrosinase 2.81923
DENR density-regulated protein 2.80132
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.80059
NUP133 nucleoporin 133kDa 2.79852
HAX1 HCLS1 associated protein X-1 2.79403
GSTZ1 glutathione S-transferase zeta 1 2.78416
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.76819
ASNS asparagine synthetase (glutamine-hydrolyzing) 2.7537
PDCD6 programmed cell death 6 2.75199
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.74805
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 2.74402
FOSL1 FOS-like antigen 1 2.74066
RSU1 Ras suppressor protein 1 2.7393
GFPT1 glutamine--fructose-6-phosphate transaminase 1 2.73686
TAOK3 TAO kinase 3 2.73417
LGALS7B lectin, galactoside-binding, soluble, 7B 2.72924
MTX2 metaxin 2 2.72303
NBAS neuroblastoma amplified sequence 2.69613
THADA thyroid adenoma associated 2.69022
DUSP10 dual specificity phosphatase 10 2.67535
ACAD10 acyl-CoA dehydrogenase family, member 10 2.67052
H2BC21 H2B clustered histone 21 2.64174
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 2.64129
IGFBP4 insulin-like growth factor binding protein 4 2.63617
GCC1 GRIP and coiled-coil domain containing 1 2.62957
LSR lipolysis stimulated lipoprotein receptor 2.62095
UBE3C ubiquitin protein ligase E3C 2.61177
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 2.58457
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 2.55169
MARS1 methionyl-tRNA synthetase 1 2.55092
ITPKC inositol-trisphosphate 3-kinase C 2.54145
LRRC59 leucine rich repeat containing 59 2.53355
AP1B1 adaptor-related protein complex 1, beta 1 subunit 2.53335
GSTA4 glutathione S-transferase alpha 4 2.53201
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 2.53145
MEAF6 MYST/Esa1-associated factor 6 2.52733
PHKB phosphorylase kinase, beta 2.52636
RLF rearranged L-myc fusion 2.50512
CD151 CD151 molecule (Raph blood group) 2.50488
PRELID3B PRELI domain containing 3B 2.50238
TARS1 threonyl-tRNA synthetase 1 2.49499
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 2.49235
AP5M1 adaptor-related protein complex 5, mu 1 subunit 2.48876
USP18 ubiquitin specific peptidase 18 2.48775
TNIP1 TNFAIP3 interacting protein 1 2.48761
THTPA thiamine triphosphatase 2.48443
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 2.48082
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 2.46935
NRIP1 nuclear receptor interacting protein 1 2.46687
BRD9 bromodomain containing 9 2.46246
GARS1 glycyl-tRNA synthetase 1 2.46186
SYNGAP1 synaptic Ras GTPase activating protein 1 2.45915
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 2.45759
ZNF212 zinc finger protein 212 2.45042
ARF5 ADP-ribosylation factor 5 2.44743
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 2.44734
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) 2.44716
ACTC1 actin, alpha, cardiac muscle 1 2.43704
HDHD5 haloacid dehalogenase like hydrolase domain containing 5 2.43054
LETMD1 LETM1 domain containing 1 2.42663
SPG11 spastic paraplegia 11 (autosomal recessive) 2.4264
KCTD5 potassium channel tetramerization domain containing 5 2.41637
NOP53 NOP53 ribosome biogenesis factor 2.41234
RHOH ras homolog family member H 2.40938
ZCCHC8 zinc finger, CCHC domain containing 8 2.40729
KIFAP3 kinesin-associated protein 3 2.40492
ZNF146 zinc finger protein 146 2.40383
ARL8B ADP-ribosylation factor-like 8B 2.40074
PGLS 6-phosphogluconolactonase 2.3981
CREG1 cellular repressor of E1A-stimulated genes 1 2.39733
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.39536
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.39279
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 2.39155
TNRC6B trinucleotide repeat containing 6B 2.39051
KRT1 keratin 1, type II 2.3872
PFDN2 prefoldin subunit 2 2.36953
CHGB chromogranin B 2.3648
TNNT2 troponin T type 2 (cardiac) 2.36304
MLEC malectin 2.36063
NDEL1 nudE neurodevelopment protein 1-like 1 2.35783
CXCL13 chemokine (C-X-C motif) ligand 13 2.35776
GIPC1 GIPC PDZ domain containing family, member 1 2.34147
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 2.33103
RSRC2 arginine/serine-rich coiled-coil 2 2.32583
BBC3 BCL2 binding component 3 2.32571
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.31916
JARID2 jumonji, AT rich interactive domain 2 2.31839
CNTNAP2 contactin associated protein-like 2 2.31796
CD81 CD81 molecule 2.31642
CDK5 cyclin-dependent kinase 5 2.31408
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 2.31287
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 2.31287
RAB3A RAB3A, member RAS oncogene family 2.31092
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 2.30962
TSEN2 TSEN2 tRNA splicing endonuclease subunit 2.30844
SDK2 sidekick cell adhesion molecule 2 2.30507
PEPD peptidase D 2.30355
HBEGF heparin-binding EGF-like growth factor 2.29856
NAMPT nicotinamide phosphoribosyltransferase 2.29694
SNX17 sorting nexin 17 2.29671
TMEM80 transmembrane protein 80 2.28688
FXR2 fragile X mental retardation, autosomal homolog 2 2.2833
IFRD1 interferon-related developmental regulator 1 2.27528
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 2.2684
SH3GLB2 SH3-domain GRB2-like endophilin B2 2.25693
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 2.24773
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.24115
TFF3 trefoil factor 3 (intestinal) 2.22982
PRAME preferentially expressed antigen in melanoma 2.22934
NSF N-ethylmaleimide-sensitive factor 2.22911
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.20787
CYCS cytochrome c, somatic 2.2068
AMPH amphiphysin 2.20626
ZNF394 zinc finger protein 394 2.20572
MRPS17 mitochondrial ribosomal protein S17 2.20563
CYTH2 cytohesin 2 2.20477
SLC30A9 solute carrier family 30 (zinc transporter), member 9 2.19882
KRT6B keratin 6B, type II 2.19564
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 2.18917
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.18865
LPXN leupaxin 2.1803
TM4SF20 transmembrane 4 L six family member 20 2.17775
MLANA melan-A 2.17494
RBM28 RNA binding motif protein 28 2.17246
ATP9B ATPase, class II, type 9B 2.17191
CDK5RAP3 CDK5 regulatory subunit associated protein 3 2.16508
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 2.16368
ENO2 enolase 2 (gamma, neuronal) 2.16346
PSEN1 presenilin 1 2.16277
TEX2 testis expressed 2 2.14984
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 2.14904
TFF1 trefoil factor 1 2.14799
SPRR1B small proline-rich protein 1B 2.14496
SMC6 structural maintenance of chromosomes 6 2.1373
RAB38 RAB38, member RAS oncogene family 2.12935
EIF1 eukaryotic translation initiation factor 1 2.12796
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 2.12558
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 2.12125
PAIP1 poly(A) binding protein interacting protein 1 2.11224
CTSZ cathepsin Z 2.11094
KDM7A lysine (K)-specific demethylase 7A 2.11057
RABAC1 Rab acceptor 1 (prenylated) 2.10668
TBCB tubulin folding cofactor B 2.10196
NADSYN1 NAD synthetase 1 2.09132
CAMK1 calcium/calmodulin-dependent protein kinase I 2.09126
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.09058
SLC35B1 solute carrier family 35, member B1 2.08719
EIF4H eukaryotic translation initiation factor 4H 2.08701
WDR37 WD repeat domain 37 2.08615
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 2.083
MYLIP myosin regulatory light chain interacting protein 2.08291
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 2.07867
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 2.07227
ACSF2 acyl-CoA synthetase family member 2 2.07217
MICALL1 MICAL-like 1 2.06736
UFC1 ubiquitin-fold modifier conjugating enzyme 1 2.06039
WDR33 WD repeat domain 33 2.05758
CIB2 calcium and integrin binding family member 2 2.05531
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 2.05444
NAIP NLR family, apoptosis inhibitory protein 2.05319
GUCY2C guanylate cyclase 2C 2.05214
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 2.04984
KLF10 Kruppel-like factor 10 2.04978
YARS1 tyrosyl-tRNA synthetase 1 2.04915
MKRN2 makorin ring finger protein 2 2.04693
KLC1 kinesin light chain 1 2.04552
POU2AF1 POU class 2 associating factor 1 2.04385
RHOA ras homolog family member A 2.04383
CKAP4 cytoskeleton-associated protein 4 2.04377
TMEM106B transmembrane protein 106B 2.04375
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 2.04191
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.0415
APMAP adipocyte plasma membrane associated protein 2.04049
FKBP11 FK506 binding protein 11, 19 kDa 2.0401
RUBCN rubicon autophagy regulator 2.03819
NFE2L2 nuclear factor, erythroid 2-like 2 2.03542
PPIE peptidylprolyl isomerase E (cyclophilin E) 2.03285
NFIL3 nuclear factor, interleukin 3 regulated 2.02805
MAGEA8 melanoma antigen family A8 2.02316
PYGB phosphorylase, glycogen; brain 2.01711
REXO2 RNA exonuclease 2 2.01435
ELOVL5 ELOVL fatty acid elongase 5 2.01416
CSK c-src tyrosine kinase 2.01355
SDHAF3 succinate dehydrogenase complex assembly factor 3 2.01267
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.01254
ANKRD36C ankyrin repeat domain 36C 2.01162
MLPH melanophilin 2.00644
SMTN smoothelin 2.00576
ZNF451 zinc finger protein 451 2.00426
GRB2 growth factor receptor-bound protein 2 2.00389
LGSN lengsin, lens protein with glutamine synthetase domain 2.00209
FOCAD focadhesin 2.00133
DOCK6 dedicator of cytokinesis 6 2.00081

decreased expression

Symbol Name Standardized Value
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -4.75809
SMNDC1 survival motor neuron domain containing 1 -4.60413
S100A8 S100 calcium binding protein A8 -4.53222
SLC35F2 solute carrier family 35, member F2 -4.5107
RPN1 ribophorin I -4.43369
VDAC1 voltage-dependent anion channel 1 -4.26435
DCK deoxycytidine kinase -4.14892
TOPBP1 topoisomerase (DNA) II binding protein 1 -4.14152
RPA3 replication protein A3, 14kDa -4.13942
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -4.09689
KIFBP kinesin family binding protein -4.09585
MTFR1 mitochondrial fission regulator 1 -3.96661
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.93345
IGFBP7 insulin-like growth factor binding protein 7 -3.91537
PGRMC1 progesterone receptor membrane component 1 -3.64761
HSPA1A heat shock 70kDa protein 1A -3.58477
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.57329
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.46072
PLK1 polo-like kinase 1 -3.42408
SHMT1 serine hydroxymethyltransferase 1 (soluble) -3.41022
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -3.40829
ENY2 enhancer of yellow 2 homolog (Drosophila) -3.39075
NUBP2 nucleotide binding protein 2 -3.37303
CCNB2 cyclin B2 -3.37075
PHTF1 putative homeodomain transcription factor 1 -3.33265
LYRM1 LYR motif containing 1 -3.32437
WDR73 WD repeat domain 73 -3.24518
EXO1 exonuclease 1 -3.17757
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.17606
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -3.14224
BTBD1 BTB (POZ) domain containing 1 -3.13686
JRKL JRK-like -3.13353
CRYZ crystallin, zeta (quinone reductase) -3.13306
INSIG1 insulin induced gene 1 -3.10798
UBA7 ubiquitin-like modifier activating enzyme 7 -3.10126
SPC25 SPC25, NDC80 kinetochore complex component -3.10052
RPP30 ribonuclease P/MRP 30kDa subunit -3.08541
MACO1 macoilin 1 -3.07657
KIF2C kinesin family member 2C -3.0487
KIF18B kinesin family member 18B -3.02702
CSF3R colony stimulating factor 3 receptor (granulocyte) -3.0264
ZNF200 zinc finger protein 200 -3.02522
CXCL12 chemokine (C-X-C motif) ligand 12 -2.98117
FLCN folliculin -2.96475
OIP5 Opa interacting protein 5 -2.94598
ATAD2 ATPase family, AAA domain containing 2 -2.9398
DEPDC1 DEP domain containing 1 -2.91251
PARP16 poly (ADP-ribose) polymerase family, member 16 -2.9084
MOCS2 molybdenum cofactor synthesis 2 -2.90433
JRK Jrk homolog (mouse) -2.90402
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.8849
CASP8AP2 caspase 8 associated protein 2 -2.88455
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.88403
DACT1 dishevelled-binding antagonist of beta-catenin 1 -2.86325
HMGN3 high mobility group nucleosomal binding domain 3 -2.84446
HPD 4-hydroxyphenylpyruvate dioxygenase -2.838
PAQR4 progestin and adipoQ receptor family member IV -2.8316
UBXN8 UBX domain protein 8 -2.82901
CCNC cyclin C -2.8194
AP3S1 adaptor-related protein complex 3, sigma 1 subunit -2.8152
CCNL2 cyclin L2 -2.77734
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.77387
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 -2.76075
MSMO1 methylsterol monooxygenase 1 -2.74629
SIGLEC15 sialic acid binding Ig-like lectin 15 -2.72901
DCLRE1B DNA cross-link repair 1B -2.72671
KIF11 kinesin family member 11 -2.7222
POLK polymerase (DNA directed) kappa -2.72173
ADD3 adducin 3 (gamma) -2.72091
KHDC4 KH domain containing 4, pre-mRNA splicing factor -2.70872
ATRIP ATR interacting protein -2.70633
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -2.69869
POLD3 polymerase (DNA-directed), delta 3, accessory subunit -2.68759
SOD3 superoxide dismutase 3, extracellular -2.68576
CHMP6 charged multivesicular body protein 6 -2.65272
TM9SF3 transmembrane 9 superfamily member 3 -2.64644
TCEAL4 transcription elongation factor A (SII)-like 4 -2.63436
FBN1 fibrillin 1 -2.62135
ABLIM3 actin binding LIM protein family, member 3 -2.60782
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit -2.60322
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.60164
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.59931
LCAT lecithin-cholesterol acyltransferase -2.59825
TOMM34 translocase of outer mitochondrial membrane 34 -2.59674
RBM22 RNA binding motif protein 22 -2.5963
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -2.59232
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -2.58261
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -2.57399
CFP complement factor properdin -2.5637
PEX11A peroxisomal biogenesis factor 11 alpha -2.55277
SP140L SP140 nuclear body protein-like -2.54655
SGK1 serum/glucocorticoid regulated kinase 1 -2.54411
RETN resistin -2.53545
MAT2B methionine adenosyltransferase II, beta -2.53444
CTRB1 chymotrypsinogen B1 -2.53126
MORF4L1 mortality factor 4 like 1 -2.52928
GCGR glucagon receptor -2.51864
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.51049
AK8 adenylate kinase 8 -2.49793
RAB36 RAB36, member RAS oncogene family -2.49175
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.48712
CUTC cutC copper transporter -2.48342
SPPL2A signal peptide peptidase like 2A -2.48283
SHBG sex hormone-binding globulin -2.48151
HELLS helicase, lymphoid-specific -2.46809
GRK5 G protein-coupled receptor kinase 5 -2.46417
APOA2 apolipoprotein A-II -2.4617
COX7B cytochrome c oxidase subunit VIIb -2.45957
SNRPG small nuclear ribonucleoprotein polypeptide G -2.45298
ZBTB16 zinc finger and BTB domain containing 16 -2.45204
CARHSP1 calcium regulated heat stable protein 1, 24kDa -2.45116
HIRIP3 HIRA interacting protein 3 -2.44594
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.44354
RCC1 regulator of chromosome condensation 1 -2.44346
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 -2.44332
FMR1 fragile X mental retardation 1 -2.44143
CDC25C cell division cycle 25C -2.43794
ZMYM3 zinc finger, MYM-type 3 -2.42691
PRCP prolylcarboxypeptidase (angiotensinase C) -2.41973
CCNH cyclin H -2.41937
EBAG9 estrogen receptor binding site associated, antigen, 9 -2.41794
LYZ lysozyme -2.41069
EMP2 epithelial membrane protein 2 -2.40763
CENPI centromere protein I -2.40332
SF3A3 splicing factor 3a, subunit 3, 60kDa -2.39838
FOXM1 forkhead box M1 -2.39742
CFI complement factor I -2.39344
PFAS phosphoribosylformylglycinamidine synthase -2.39258
GTF3A general transcription factor IIIA -2.39155
DAZAP2 DAZ associated protein 2 -2.38869
HADH hydroxyacyl-CoA dehydrogenase -2.388
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) -2.38648
BORA bora, aurora kinase A activator -2.38282
GFRA1 GDNF family receptor alpha 1 -2.38191
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -2.37877
MSLN mesothelin -2.37688
SCD stearoyl-CoA desaturase (delta-9-desaturase) -2.3759
CENPS-CORT CENPS-CORT readthrough -2.37518
FOXJ2 forkhead box J2 -2.37233
MDC1 mediator of DNA-damage checkpoint 1 -2.37171
PALMD palmdelphin -2.36871
PDE1A phosphodiesterase 1A, calmodulin-dependent -2.36765
CTRB2 chymotrypsinogen B2 -2.36556
CNN2 calponin 2 -2.35607
CLU clusterin -2.35456
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.35363
ADI1 acireductone dioxygenase 1 -2.35143
GSDMD gasdermin D -2.34307
PKD2L1 polycystic kidney disease 2-like 1 -2.33943
TXNDC9 thioredoxin domain containing 9 -2.33914
ASGR2 asialoglycoprotein receptor 2 -2.33857
BMPR1A bone morphogenetic protein receptor, type IA -2.33479
PRELP proline/arginine-rich end leucine-rich repeat protein -2.33363
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -2.33278
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 -2.33179
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -2.33121
CTRL chymotrypsin-like -2.32859
DONSON downstream neighbor of SON -2.32829
RIDA reactive intermediate imine deaminase A homolog -2.32735
KITLG KIT ligand -2.30351
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -2.30272
BFAR bifunctional apoptosis regulator -2.30196
WASHC5 WASH complex subunit 5 -2.29703
DCLRE1A DNA cross-link repair 1A -2.29417
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -2.29222
MTAP methylthioadenosine phosphorylase -2.28896
ZXDC ZXD family zinc finger C -2.2853
GP1BA glycoprotein Ib (platelet), alpha polypeptide -2.28408
AHSG alpha-2-HS-glycoprotein -2.2839
PEX3 peroxisomal biogenesis factor 3 -2.28351
LHX1 LIM homeobox 1 -2.27671
GTSE1 G-2 and S-phase expressed 1 -2.272
NPC1L1 NPC1-like 1 -2.27191
EXOSC9 exosome component 9 -2.27042
TMA7 translation machinery associated 7 homolog (S. cerevisiae) -2.27009
WDR76 WD repeat domain 76 -2.26873
ECM2 extracellular matrix protein 2, female organ and adipocyte specific -2.2605
IL17RB interleukin 17 receptor B -2.25723
RBL1 retinoblastoma-like 1 -2.25553
GOLT1B golgi transport 1B -2.25413
POGLUT2 protein O-glucosyltransferase 2 -2.25349
CCNF cyclin F -2.25217
SLC68A1 solute carrier family 68 member 1 -2.25205
FASN fatty acid synthase -2.25155
LOC102724594 splicing factor U2AF 35 kDa subunit -2.24683
SHCBP1 SHC SH2-domain binding protein 1 -2.24481
MKI67 marker of proliferation Ki-67 -2.24362
SCML1 sex comb on midleg-like 1 (Drosophila) -2.24348
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -2.24179
SLC43A3 solute carrier family 43, member 3 -2.24159
COX6C cytochrome c oxidase subunit VIc -2.24149
CTRC chymotrypsin C (caldecrin) -2.23047
MAT1A methionine adenosyltransferase I, alpha -2.22885
TNP1 transition protein 1 (during histone to protamine replacement) -2.22681
NGRN neugrin, neurite outgrowth associated -2.22551
USP22 ubiquitin specific peptidase 22 -2.22183
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -2.21964
MCMBP minichromosome maintenance complex binding protein -2.21937
ANXA4 annexin A4 -2.21829
NLGN4X neuroligin 4, X-linked -2.21691
OSBPL11 oxysterol binding protein-like 11 -2.21193
NFU1 NFU1 iron-sulfur cluster scaffold -2.21166
ADIRF adipogenesis regulatory factor -2.20546
FRK fyn-related Src family tyrosine kinase -2.2043
KIF14 kinesin family member 14 -2.20276
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -2.19976
MOK MOK protein kinase -2.19933
RFC3 replication factor C (activator 1) 3, 38kDa -2.19372
VAV3 vav 3 guanine nucleotide exchange factor -2.19053
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -2.18923
PRRX2 paired related homeobox 2 -2.18828
PSMC3IP PSMC3 interacting protein -2.18747
REXO5 RNA exonuclease 5 -2.18626
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 -2.18606
RAB20 RAB20, member RAS oncogene family -2.18446
VBP1 von Hippel-Lindau binding protein 1 -2.18361
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 -2.18044
LAPTM4A lysosomal protein transmembrane 4 alpha -2.17914
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) -2.17344
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) -2.16994
SLC66A2 solute carrier family 66 member 2 -2.1647
WBP1L WW domain binding protein 1-like -2.1615
DDB2 damage-specific DNA binding protein 2, 48kDa -2.15895
PLG plasminogen -2.15634
SFXN3 sideroflexin 3 -2.15614
MGMT O-6-methylguanine-DNA methyltransferase -2.15457
PTPN9 protein tyrosine phosphatase, non-receptor type 9 -2.15377
HOXC4 homeobox C4 -2.15167
ACTL7A actin-like 7A -2.1493
GATA4 GATA binding protein 4 -2.14811
SYBU syntabulin (syntaxin-interacting) -2.14675
GYG1 glycogenin 1 -2.14668
CRISP3 cysteine-rich secretory protein 3 -2.14627
ASF1B anti-silencing function 1B histone chaperone -2.14538
SPAG5 sperm associated antigen 5 -2.14396
RFX2 regulatory factor X, 2 (influences HLA class II expression) -2.14253
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma -2.13791
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.13747
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) -2.13706
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.137
CD24 CD24 molecule -2.13365
CISD1 CDGSH iron sulfur domain 1 -2.13264
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -2.12978
TK1 thymidine kinase 1, soluble -2.1274
CLEC1B C-type lectin domain family 1, member B -2.12718
APOH apolipoprotein H (beta-2-glycoprotein I) -2.12434
STIL SCL/TAL1 interrupting locus -2.12303
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -2.12222
NEMP1 nuclear envelope integral membrane protein 1 -2.12212
PBK PDZ binding kinase -2.11923
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.11881
HMGN2 high mobility group nucleosomal binding domain 2 -2.11609
TTK TTK protein kinase -2.1102
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 -2.10965
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -2.10746
CBX3 chromobox homolog 3 -2.10684
LMCD1 LIM and cysteine-rich domains 1 -2.10366
MED7 mediator complex subunit 7 -2.10256
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 -2.1
KRABD4 KRAB domain containing 4 -2.09748
TOR1A torsin family 1, member A (torsin A) -2.09621
DENND1A DENN/MADD domain containing 1A -2.0944
AMBP alpha-1-microglobulin/bikunin precursor -2.09245
NFRKB nuclear factor related to kappaB binding protein -2.09068
PARPBP PARP1 binding protein -2.09052
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -2.08863
RFWD3 ring finger and WD repeat domain 3 -2.08788
TENT5A terminal nucleotidyltransferase 5A -2.08701
CPZ carboxypeptidase Z -2.08462
RWDD2B RWD domain containing 2B -2.08264
SCML2 sex comb on midleg-like 2 (Drosophila) -2.07901
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 -2.07763
CEP162 centrosomal protein 162kDa -2.07451
DSN1 DSN1, MIS12 kinetochore complex component -2.07309
RPL18A ribosomal protein L18a -2.07162
LPCAT3 lysophosphatidylcholine acyltransferase 3 -2.06986
ZNF512B zinc finger protein 512B -2.06982
NPIPB5 nuclear pore complex interacting protein family, member B5 -2.06947
RNF38 ring finger protein 38 -2.06537
RCOR3 REST corepressor 3 -2.06121
BICC1 BicC family RNA binding protein 1 -2.06103
NOP14 NOP14 nucleolar protein -2.05758
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific -2.05756
GGT5 gamma-glutamyltransferase 5 -2.05504
HSF2BP heat shock transcription factor 2 binding protein -2.05112
TROAP trophinin associated protein -2.04979
SDC4 syndecan 4 -2.04572
SH2D4A SH2 domain containing 4A -2.04424
PALB2 partner and localizer of BRCA2 -2.04257
AOX1 aldehyde oxidase 1 -2.04191
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.04174
DND1 DND microRNA-mediated repression inhibitor 1 -2.04106
FNBP4 formin binding protein 4 -2.03835
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 -2.03693
NKX2-8 NK2 homeobox 8 -2.03509
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -2.03444
PROS1 protein S (alpha) -2.02824
C1RL complement component 1, r subcomponent-like -2.02798
CELA3B chymotrypsin-like elastase family, member 3B -2.0273
BEGAIN brain-enriched guanylate kinase-associated -2.0242
PHC2 polyhomeotic homolog 2 (Drosophila) -2.02182
TIMCC TIM double twin CX3C motif chaperone -2.02151
HNRNPK heterogeneous nuclear ribonucleoprotein K -2.01877
VTN vitronectin -2.01741
ZNF778 zinc finger protein 778 -2.01498
MKNK2 MAP kinase interacting serine/threonine kinase 2 -2.01454
MCM4 minichromosome maintenance complex component 4 -2.01376
CCDC198 coiled-coil domain containing 198 -2.01339
LOX lysyl oxidase -2.01315
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 -2.01291
FEN1 flap structure-specific endonuclease 1 -2.0127
POLH polymerase (DNA directed), eta -2.01168
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -2.0093
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 -2.00802
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 -2.00684
EML4 echinoderm microtubule associated protein like 4 -2.00618
PARP6 poly (ADP-ribose) polymerase family, member 6 -2.00566
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -2.00511
NEK2 NIMA-related kinase 2 -2.00366
CELA3A chymotrypsin-like elastase family, member 3A -2.00167