CRCGN015_MCF10A_48H:L09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description iq 10.65 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN015_MCF10A_48H:L09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.63149
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.57629
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.31801
STK10 serine/threonine kinase 10 2.31431
NOP16 NOP16 nucleolar protein 2.10682

decreased expression

Symbol Name Standardized Value
HSPA8 heat shock 70kDa protein 8 -5.10266
LYPLA1 lysophospholipase I -5.08432
IGFBP7 insulin-like growth factor binding protein 7 -4.20899
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -3.30245
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough -2.90718
MRPL15 mitochondrial ribosomal protein L15 -2.89923
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H -2.82098
PLK2 polo-like kinase 2 -2.78409
KRT7 keratin 7, type II -2.28012
RB1CC1 RB1-inducible coiled-coil 1 -2.19456
COMP cartilage oligomeric matrix protein -2.15613
TSG101 tumor susceptibility 101 -2.01993
PDLIM1 PDZ and LIM domain 1 -2.00933