CRCGN015_MCF10A_48H:L16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,3-dibromo-1-propanol 100.8 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

12 genes differentially expressed following the CRCGN015_MCF10A_48H:L16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ZW10 zw10 kinetochore protein 3.85656
AMDHD2 amidohydrolase domain containing 2 3.77481
GRWD1 glutamate-rich WD repeat containing 1 3.45406
HLA-DRA major histocompatibility complex, class II, DR alpha 3.30224
KDM5A lysine (K)-specific demethylase 5A 2.76952
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.15692
HBA1 hemoglobin, alpha 1 2.05739

decreased expression

Symbol Name Standardized Value
PLS1 plastin 1 -3.39367
SMC1A structural maintenance of chromosomes 1A -2.15897
ZBTB35 zinc finger and BTB domain containing 35 -2.1048
SNX7 sorting nexin 7 -2.05764
SF3B2 splicing factor 3b, subunit 2, 145kDa -2.00309