CRCGN015_MCF10A_48H:L20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 3,3'-dichlorobenzidine 32.26 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN015_MCF10A_48H:L20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
IPO13 importin 13 2.96412
GATA3 GATA binding protein 3 2.92855
CDPF1 cysteine-rich, DPF motif domain containing 1 2.56767
SOCS2 suppressor of cytokine signaling 2 2.18701
IL1A interleukin 1, alpha 2.06469
ZNF217 zinc finger protein 217 2.00999

decreased expression

Symbol Name Standardized Value
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -3.39636
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -3.0765
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.00943
RAB4A RAB4A, member RAS oncogene family -2.66718
HSPA1A heat shock 70kDa protein 1A -2.49637
CCNB2 cyclin B2 -2.31565
BCCIP BRCA2 and CDKN1A interacting protein -2.28095
SYCP2 synaptonemal complex protein 2 -2.25212
COG4 component of oligomeric golgi complex 4 -2.19707
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.15709
MELK maternal embryonic leucine zipper kinase -2.06244